SCHEMBL851318

SCHEMBL851318

CCCCCCn1c2ccc(C=O)cc2c2cc(C=O)ccc21

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 4/20 0.56
PSEN1 P49768 6/20 0.49
PSEN2 P49810 6/20 0.49
APH1B Q8WW43 6/20 0.49
NCSTN Q92542 6/20 0.49
APH1A Q96BI3 6/20 0.49
PSENEN Q9NZ42 6/20 0.49
CNR2 P34972 7/20 0.48
RORA P35398 1/20 0.45
RORC P51449 1/20 0.45
RORB Q92753 1/20 0.45
CNR1 P21554 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6279820 1.00 PTGER4 (0.56) PTGER4PSEN1PSEN2APH1BNCSTN
SCHEMBL29794198 1.00 PTGER4 (0.56) PTGER4PSEN1PSEN2APH1BNCSTN
SCHEMBL29794182 1.00 PTGER4 (0.56) PTGER4PSEN1PSEN2APH1BNCSTN
SCHEMBL6281257 1.00 PTGER4 (0.56) PTGER4PSEN1PSEN2APH1BNCSTN
SCHEMBL6775173 1.00 PTGER4 (0.56) PTGER4PSEN1PSEN2APH1BNCSTN
SCHEMBL6275738 1.00 PTGER4 (0.56) PTGER4PSEN1PSEN2APH1BNCSTN
SCHEMBL29808759 1.00 PTGER4 (0.56) PTGER4PSEN1PSEN2APH1BNCSTN
SCHEMBL28615487 1.00 PTGER4 (0.56) PTGER4PSEN1PSEN2APH1BNCSTN
SCHEMBL6279947 1.00 PTGER4 (0.56) PTGER4PSEN1PSEN2APH1BNCSTN
SCHEMBL28320942 1.00 PTGER4 (0.56) PTGER4PSEN1PSEN2APH1BNCSTN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114805796-B Two-dimensional strong fluorescence polyaniline material with metal ion detection performance and preparation method thereof 武汉大学 2023-08-22 CN claimed
CN-114805796-A Two-dimensional strong-fluorescence polyaniline material with metal ion detection performance and preparation method thereof 武汉大学 2022-07-29 CN claimed
CN-110183626-B Conjugated polymer and preparation method and application thereof 齐鲁工业大学 2022-02-25 CN claimed
CN-110183626-A A kind of conjugated polymer and the preparation method and application thereof 齐鲁工业大学 2019-08-30 CN claimed
CN-114805796-B Two-dimensional strong fluorescence polyaniline material with metal ion detection performance and preparation method thereof 武汉大学 2023-08-22 CN disclosed
CN-114805796-A Two-dimensional strong-fluorescence polyaniline material with metal ion detection performance and preparation method thereof 武汉大学 2022-07-29 CN disclosed
CN-110183626-B Conjugated polymer and preparation method and application thereof 齐鲁工业大学 2022-02-25 CN disclosed
CN-113234008-A Fluorescent organic matter, fluorescent dye and sequential color light emission regulation method 太原理工大学 2021-08-10 CN disclosed
CN-110183626-A A kind of conjugated polymer and the preparation method and application thereof 齐鲁工业大学 2019-08-30 CN disclosed
CN-102633781-B N-alkyl group-3, 6-di-(2-quinoline) vinyl) carbazole and preparation method thereof UNIV HEILONGJIANG 2013-12-25 CN disclosed
CN-102633781-A N-alkyl group-3, 6-di-(2-quinoline) vinyl) carbazole and preparation method thereof UNIV HEILONGJIANG 2012-08-15 CN disclosed
US-8143465-B2 Soluble branched triaroylbenzene-based polymer and its synthetic method THE HONG KONG UNIVERSITY OF SCIENCE & TECHNOLOGY (CN) 2012-03-27 US disclosed
US-6503998-B2 Nonlinear Optical (nlo) materials, sulfon-diol-ether derivatives NATIONAL SCIENCE COUNCIL (TW) 2003-01-07 US disclosed
US-20020115869-A1 Lambda-shaped carbazole and main-chain NLO polyurethane containing the same NATIONAL SCIENCE COUNCIL (TW) 2002-08-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020115869-A1 Lambda-shaped carbazole and main-chain NLO polyurethane containing the same POLL, POLK, LBR PTGER4 1147/4885PSEN1 3770/4885PSEN2 3157/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.