Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR1 | P30872 | 1/20 | 0.35 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.35 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.35 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.35 |
| ▸ | FGF1 | P05230 | 2/20 | 0.33 |
| ▸ | FGF2 | P09038 | 2/20 | 0.33 |
| ▸ | VEGFA | P15692 | 2/20 | 0.33 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.32 |
| ▸ | CDC25B | P30305 | 2/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | GJB2 | P29033 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.30 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8513450 | 1.00 | SSTR1 (0.35) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL8513204 | 0.90 | SSTR1 (0.35) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL14932066 | 0.85 | SSTR1 (0.37) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL14932065 | 0.85 | SSTR1 (0.37) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL8513985 | 0.84 | PTPN1 (0.36) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL8513989 | 0.84 | PTPN1 (0.36) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL2014901 | 0.81 | SLC6A2 (0.35) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL2014900 | 0.81 | SLC6A2 (0.35) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL8515951 | 0.75 | SLC6A2 (0.35) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL8515950 | 0.75 | SLC6A2 (0.35) | SSTR1SSTR2SSTR4SSTR3SSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2457573-A1 | Methods of use of glycomimetics with replacements for hexoses and N-Acetyl hexosamines | GlycoMimetics, Inc. (US) | 2012-05-30 | — | — | EP | disclosed |