Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC2 | Q13490 | 12/20 | 0.49 |
| ▸ | XIAP | P98170 | 9/20 | 0.46 |
| ▸ | BIRC3 | Q13489 | 3/20 | 0.46 |
| ▸ | CASP9 | P55211 | 1/20 | 0.46 |
| ▸ | MLX | Q9UH92 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8514536 | 0.91 | BIRC2 (0.50) | BIRC2XIAPBIRC3CASP9MLX | |
| SCHEMBL8514532 | 0.83 | BIRC2 (0.60) | BIRC2XIAPBIRC3CASP9 | |
| SCHEMBL3729230 | 0.82 | ACE (0.47) | BIRC2XIAPBIRC3MLXACE | |
| SCHEMBL4562933 | 0.81 | BIRC2 (0.56) | BIRC2XIAPBIRC3CASP9 | |
| SCHEMBL3732909 | 0.77 | ACE (0.52) | BIRC2XIAPBIRC3ACEELANE | |
| SCHEMBL13260002 | 0.76 | XIAP (0.58) | BIRC2XIAPBIRC3CASP9 | |
| SCHEMBL4315737 | 0.73 | XIAP (0.70) | BIRC2XIAPBIRC3CASP9 | |
| SCHEMBL30249738 | 0.73 | XIAP (0.70) | BIRC2XIAPBIRC3CASP9 | |
| SCHEMBL14421116 | 0.73 | XIAP (0.70) | BIRC2XIAPBIRC3CASP9 | |
| SCHEMBL14421200 | 0.73 | XIAP (0.70) | BIRC2XIAPBIRC3CASP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2457895-A1 | Tetrapeptide analogs | Idun Pharmaceuticals, Inc. (US) | 2012-05-30 | — | — | EP | disclosed |