Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | FBP1 | P09467 | 2/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8512130 | 1.00 | CYP1A2 (0.53) | CYP1A2CYP2C19CYP2D6CYP3A4MAPK1 | |
| SCHEMBL15463349 | 1.00 | CYP1A2 (0.53) | CYP1A2CYP2C19CYP2D6CYP3A4MAPK1 | |
| SCHEMBL8510381 | 1.00 | CYP1A2 (0.53) | CYP1A2CYP2C19CYP2D6CYP3A4MAPK1 | |
| SCHEMBL8512674 | 1.00 | CYP1A2 (0.53) | CYP1A2CYP2C19CYP2D6CYP3A4MAPK1 | |
| SCHEMBL8511312 | 1.00 | CYP1A2 (0.53) | CYP1A2CYP2C19CYP2D6CYP3A4MAPK1 | |
| SCHEMBL30287610 | 1.00 | CYP1A2 (0.53) | CYP1A2CYP2C19CYP2D6CYP3A4MAPK1 | |
| SCHEMBL8512840 | 1.00 | CYP1A2 (0.53) | CYP1A2CYP2C19CYP2D6CYP3A4MAPK1 | |
| SCHEMBL3441209 | 1.00 | CYP1A2 (0.53) | CYP1A2CYP2C19CYP2D6CYP3A4MAPK1 | |
| SCHEMBL31279597 | 1.00 | CYP1A2 (0.53) | CYP1A2CYP2C19CYP2D6CYP3A4MAPK1 | |
| SCHEMBL30287604 | 0.99 | CYP1A2 (0.54) | CYP1A2CYP2C19CYP2D6CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2439236-B1 | RUBBER COMPOSITION | BRIDGESTONE CORP (JP) | 2014-10-01 | — | — | EP | disclosed |
| CN-102803372-A | Rubber composition | BRIDGESTONE CORP | 2012-11-28 | — | — | CN | disclosed |
| US-20120136102-A1 | RUBBER COMPOSITION | BRIDGESTONE CORPORATION (JP) | 2012-05-31 | — | — | US | disclosed |