Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 17/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 10/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 10/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 9/20 | 0.46 |
| ▸ | FAP | Q12884 | 7/20 | 0.46 |
| ▸ | PITRM1 | Q5JRX3 | 2/20 | 0.36 |
| ▸ | PREP | P48147 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9611390 | 1.00 | DPP4 (0.48) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL8514994 | 0.84 | DPP4 (0.44) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL9613487 | 0.80 | XIAP (0.40) | — | |
| SCHEMBL13944458 | 0.70 | PREP (0.50) | DPP4DPP8DPP9FAPPREP | |
| SCHEMBL8510880 | 0.69 | XIAP (0.35) | — | |
| SCHEMBL20652626 | 0.64 | DPP4 (0.65) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL16921202 | 0.64 | DPP4 (1.00) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL16079845 | 0.64 | DPP4 (1.00) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL18828991 | 0.64 | DPP4 (1.00) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL12657193 | 0.64 | DPP4 (1.00) | DPP4DPP8DPP7DPP9FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8415486-B2 | IAP inhibitors | TETRALOGIC PHARMACEUTICALS CORP. (US) | 2013-04-09 | — | — | US | disclosed |
| US-20120135990-A1 | IAP INHIBITORS | TETRALOGIC PHARMACEUTICALS CORP. (US) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135990-A1 | IAP INHIBITORS | XIAP, IAPP, BIRC5 | DPP4 34/4885DPP8 32/4885DPP7 24/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.