Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 6/20 | 0.72 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.72 |
| ▸ | PRSS2 | P07478 | 6/20 | 0.72 |
| ▸ | PRSS3 | P35030 | 6/20 | 0.72 |
| ▸ | ST14 | Q9Y5Y6 | 6/20 | 0.72 |
| ▸ | PLG | P00747 | 4/20 | 0.72 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8513660 | 1.00 | F2 (0.72) | F2PRSS1PRSS2PRSS3ST14 | |
| SCHEMBL8509291 | 0.84 | ST14 (0.52) | F2PRSS1PRSS2PRSS3ST14 | |
| SCHEMBL8511550 | 0.84 | ST14 (0.52) | F2PRSS1PRSS2PRSS3ST14 | |
| SCHEMBL851996 | 0.84 | ST14 (0.52) | F2PRSS1PRSS2PRSS3ST14 | |
| SCHEMBL851991 | 0.84 | F2 (0.58) | F2PRSS1PRSS2PRSS3ST14 | |
| SCHEMBL9880184 | 0.84 | ST14 (1.00) | F2PRSS1PRSS2PRSS3ST14 | |
| SCHEMBL852017 | 0.84 | ST14 (1.00) | F2PRSS1PRSS2PRSS3ST14 | |
| SCHEMBL851814 | 0.83 | F2 (0.78) | F2PRSS1PRSS2PRSS3ST14 | |
| SCHEMBL852204 | 0.83 | F2 (0.78) | F2PRSS1PRSS2PRSS3ST14 | |
| SCHEMBL8512887 | 0.81 | ST14 (0.52) | F2PRSS1PRSS2PRSS3ST14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432556-A1 | PROTEASE INHIBITORS | Orion Corporation (FI) | 2012-03-28 | — | — | EP | disclosed |