Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY5 | O95622 | 2/20 | 0.79 |
| ▸ | DRD1 | P21728 | 16/20 | 0.78 |
| ▸ | DRD2 | P14416 | 9/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.78 |
| ▸ | DRD5 | P21918 | 4/20 | 0.78 |
| ▸ | HPGD | P15428 | 3/20 | 0.78 |
| ▸ | MAPT | P10636 | 3/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.78 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.78 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.78 |
| ▸ | THPO | P40225 | 2/20 | 0.78 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.78 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.78 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.78 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.78 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.78 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.78 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.78 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11104888 | 0.98 | DRD1 (0.79) | ADCY5DRD1DRD2KDM4EDRD5 | |
| Bromide SCHEMBL11575582 | 0.98 | DRD1 (0.79) | ADCY5DRD1DRD2KDM4EDRD5 | |
| SCHEMBL28663486 | 0.91 | ADCY5 (0.70) | ADCY5DRD1DRD2KDM4EDRD5 | |
| SCHEMBL10745936 | 0.89 | ADCY5 (0.71) | ADCY5DRD1DRD2KDM4EDRD5 | |
| Skf-38393 SCHEMBL29389401 | 0.88 | DRD1 (1.00) | ADCY5DRD1DRD2KDM4EDRD5 | |
| Skf-38393 SCHEMBL469578 | 0.88 | DRD1 (1.00) | ADCY5DRD1DRD2KDM4EDRD5 | |
| (R)-Skf-38393 SCHEMBL7941051 | 0.88 | DRD1 (1.00) | ADCY5DRD1DRD2KDM4EDRD5 | |
| Bromide SCHEMBL10746501 | 0.88 | ADCY5 (0.70) | ADCY5DRD1DRD2KDM4EDRD5 | |
| Bromide SCHEMBL11539213 | 0.87 | DRD1 (0.75) | ADCY5DRD1DRD2KDM4EDRD5 | |
| Bromide SCHEMBL11716923 | 0.87 | ADCY5 (0.97) | ADCY5DRD1DRD2KDM4EDRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999055341-A1 | TRANSDERMAL ADMINISTRATION OF FENOLDOPAM | ELAN PHARMACEUTICALS, INC. (US) | 1999-11-04 | — | — | WO | disclosed |
| EP-0081006-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING 7,8-DIHYDROXY-1(HYDROXYPHENYL)-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE DERIVATIVES AND A BETA-ADRENERGIC BLOCKING COMPOUND | SMITHKLINE BECKMAN CORPORATION (US) | 1985-09-25 | — | — | EP | disclosed |
| EP-0081006-A1 | Pharmaceutical compositions comprising 7,8-dihydroxy-1(hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine derivatives and a beta-adrenergic blocking compound | SMITHKLINE BECKMAN CORPORATION (US) | 1983-06-15 | — | — | EP | disclosed |