SCHEMBL8517196 — predicted protein targets

Predicted protein targets (top 17)

	gene	UniProt	supporting neighbours	confidence
▸	MEN1	O00255	1/20	0.39

▸	KMT2A	Q03164	1/20	0.39

▸	EGFR	P00533	1/20	0.38

▸	EIF4A1	P60842	6/20	0.36

▸	GSK3B	P49841	1/20	0.35

▸	TGM2	P21980	1/20	0.34

▸	CA12	O43570	2/20	0.34

▸	CA1	P00915	2/20	0.34

▸	CA2	P00918	2/20	0.34

▸	CA9	Q16790	2/20	0.34

▸	CAPN9	O14815	1/20	0.34

▸	CASP3	P42574	1/20	0.34

▸	LMNA	P02545	1/20	0.34

▸	HPGD	P15428	1/20	0.34

▸	PDE4D	Q08499	1/20	0.34

▸	RET	P07949	1/20	0.34

▸	ABCG2	Q9UNQ0	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8517195	1.00	MEN1 (0.39)	MEN1KMT2AEGFREIF4A1GSK3B
SCHEMBL8012722	0.98	MEN1 (0.38)	MEN1KMT2AEGFREIF4A1GSK3B
SCHEMBL8012720	0.98	MEN1 (0.38)	MEN1KMT2AEGFREIF4A1GSK3B
SCHEMBL8010518	0.95	MEN1 (0.40)	MEN1KMT2AEGFRGSK3BTGM2
SCHEMBL8010512	0.95	MEN1 (0.40)	MEN1KMT2AEGFRGSK3BTGM2
SCHEMBL8001471	0.92	EGFR (0.40)	MEN1KMT2AEGFRGSK3BTGM2
SCHEMBL8001474	0.92	EGFR (0.40)	MEN1KMT2AEGFRGSK3BTGM2
SCHEMBL8012362	0.89	EGFR (0.38)	MEN1KMT2AEGFRGSK3BTGM2
SCHEMBL8012365	0.89	EGFR (0.38)	MEN1KMT2AEGFRGSK3BTGM2
SCHEMBL8010183	0.88	EGFR (0.39)	MEN1KMT2AEGFRGSK3BTGM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-1999051590-A1	SUBSTITUTED INDOLINONES AS KINASE INHIBITORS	BOEHRINGER INGELHEIM PHARMA KG (DE)	1999-10-14	—	—	WO	disclosed