Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | ALPL | P05186 | 1/20 | 0.51 |
| ▸ | ALPI | P09923 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14389108 | 1.00 | USP2 (0.56) | USP2PDPK1MEN1KMT2ANPC1 | |
| SCHEMBL21301179 | 0.89 | PDPK1 (0.47) | USP2PDPK1MEN1KMT2ANPC1 | |
| SCHEMBL31136387 | 0.81 | PDPK1 (0.44) | USP2PDPK1MEN1KMT2ANPC1 | |
| SCHEMBL8886107 | 0.81 | USP2 (0.52) | USP2MEN1KMT2ANPC1ALPL | |
| SCHEMBL14277889 | 0.80 | POLB (0.64) | USP2MEN1KMT2ANPC1ALPL | |
| SCHEMBL7504253 | 0.80 | POLB (0.64) | USP2MEN1KMT2ANPC1ALPL | |
| SCHEMBL7507499 | 0.77 | USP2 (0.56) | USP2MEN1KMT2ANPC1ALPL | |
| SCHEMBL14521552 | 0.76 | KMT2A (0.60) | USP2MEN1KMT2ANPC1POLB | |
| SCHEMBL30227667 | 0.75 | USP2 (0.47) | USP2MEN1KMT2ANPC1ALPL | |
| SCHEMBL30227399 | 0.75 | USP2 (0.47) | USP2MEN1KMT2ANPC1ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0617968-B1 | HIV protease inhibitors in pharmaceutical combinations for the treatment of AIDS | MERCK & CO INC (US) | 2003-01-08 | — | — | EP | disclosed |