Procymidone

Procymidone

SCHEMBL8517410

CC1(C(N)=O)CC1(C)C(=O)Nc1cc(Cl)cc(Cl)c1.CC12CC1(C)C(=O)N(c1cc(Cl)cc(Cl)c1)C2=O

nearest known ligand 0.58

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Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.58
POLB P06746 1/20 0.35
MAPT P10636 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
GRM4 Q14833 3/20 0.34
KMT2A Q03164 4/20 0.34
MEN1 O00255 3/20 0.34
ALDH1A1 P00352 3/20 0.33
RECQL P46063 1/20 0.33
USP2 O75604 1/20 0.33
PTPN11 Q06124 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6393560 0.86 GRM4 (0.43) POLBMAPTNPSR1GRM4KMT2A
Procymidone SCHEMBL23093 0.76 TSHR (1.00) TSHRKMT2AMEN1ALDH1A1USP2
SCHEMBL27362735 0.76 GRM4 (0.43) POLBMAPTNPSR1GRM4KMT2A
Procymidone SCHEMBL9806377 0.75 TSHR (0.96) TSHRKMT2AMEN1ALDH1A1USP2
SCHEMBL9420203 0.74 MEN1 (0.44) POLBMAPTNPSR1GRM4KMT2A
SCHEMBL11257765 0.66 MAPT (0.40) POLBMAPTNPSR1GRM4KMT2A
SCHEMBL11251648 0.66 MEN1 (0.44) POLBMAPTNPSR1GRM4KMT2A
SCHEMBL7737220 0.64 GRM4 (0.46) POLBMAPTNPSR1GRM4KMT2A
Chlozolinate SCHEMBL10456638 0.61 TSHR (0.56) TSHRMAPTALDH1A1USP2
SCHEMBL11517722 0.61 MEN1 (0.46) POLBMAPTNPSR1GRM4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5912208-A NONIONIC SURFACTANTS OF GLYCEROL-BASED POLYETHER HAVING A POTENTIATING EFFECT ON BACTERICIDES, INSECTICIDES, MITICIDES, HERBICIDES AND PLANT GROWTH REGULATORS; NO CHEMICAL DAMAGE WHEN A MIXTURE IS APPLIED TO CROPS KAO CORPORATION (JP) 1999-06-15 US disclosed
US-5863909-A CONSISTS OF SORBITAN/FATTY ACID ESTER SURFACTANT AND OTHER SURFACTANT SELECTED FROM RESIN ACID AND ANIONIC OLIGOMER OR POLYMER TYPE QUATERNARY AMMONIUM SALTS KAO CORPORATION (JP) 1999-01-26 US disclosed
US-5728649-A CATIONIC SURFACTANTS FOR AGRICULTURE KAO CORPORATION (JP) 1998-03-17 US disclosed