Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9311783 | 1.00 | ACACB (0.32) | ACACBCYP11B1CYP11B2P2RX7SLC5A2 | |
| SCHEMBL8517528 | 1.00 | ACACB (0.32) | ACACBCYP11B1CYP11B2P2RX7SLC5A2 | |
| SCHEMBL8517530 | 1.00 | ACACB (0.32) | ACACBCYP11B1CYP11B2P2RX7SLC5A2 | |
| SCHEMBL9312838 | 0.92 | GRM2 (0.33) | ACACBCYP11B1CYP11B2 | |
| SCHEMBL9312823 | 0.92 | GRM2 (0.33) | ACACBCYP11B1CYP11B2 | |
| SCHEMBL9312835 | 0.92 | GRM2 (0.33) | ACACBCYP11B1CYP11B2 | |
| SCHEMBL9312833 | 0.92 | GRM2 (0.33) | ACACBCYP11B1CYP11B2 | |
| SCHEMBL9311776 | 0.92 | SLC5A2 (0.33) | ACACBCYP11B1CYP11B2SLC5A2 | |
| SCHEMBL9311767 | 0.92 | SLC5A2 (0.33) | ACACBCYP11B1CYP11B2SLC5A2 | |
| SCHEMBL9311781 | 0.92 | SLC5A2 (0.33) | ACACBCYP11B1CYP11B2SLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475273-B1 | Liquid crystal mixture containing halogenated alcenyl compounds | MERCK PATENT GMBH (DE) | 1999-04-07 | — | — | EP | disclosed |
| US-5292452-A | Electrooptical devices; high dielectric anisotropy, low rotation viscosity, short response time | HOFFMANN-LA ROCHE INC. (US) | 1994-03-08 | — | — | US | disclosed |
| EP-0475273-A1 | Halogenated alcenyl compounds | F. HOFFMANN-LA ROCHE AG (CH) | 1992-03-18 | — | — | EP | disclosed |