Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.74 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | NAAA | Q02083 | 1/20 | 0.53 |
| ▸ | DGKA | P23743 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 2/20 | 0.45 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28236148 | 0.98 | TSHR (0.77) | TSHRHTR2CNAAADGKAHPGD | |
| SCHEMBL15998912 | 0.98 | TSHR (0.77) | TSHRHTR2CNAAADGKAHPGD | |
| SCHEMBL30517510 | 0.97 | TSHR (0.75) | TSHRHTR2CNAAADGKAHPGD | |
| SCHEMBL29111576 | 0.97 | TSHR (0.75) | TSHRHTR2CNAAADGKAHPGD | |
| SCHEMBL27839985 | 0.97 | TSHR (0.75) | TSHRHTR2CNAAADGKAHPGD | |
| SCHEMBL9247349 | 0.95 | TSHR (0.83) | TSHRHTR2CNAAADGKAHPGD | |
| Hexane SCHEMBL11329030 | 0.93 | TSHR (0.85) | TSHRHTR2CNAAADGKAHPGD | |
| SCHEMBL28653942 | 0.89 | TSHR (0.64) | TSHRHTR2CNAAADGKAHPGD | |
| Allyl Hexanoate SCHEMBL11653171 | 0.88 | TSHR (0.83) | TSHRHTR2CNAAADGKAPRSS1 | |
| Allyl Dodecanoate SCHEMBL4424289 | 0.87 | TSHR (0.96) | TSHRDGKAPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661310-B1 | Cyclo-olefincopolymers and process for their preparation | TICONA GMBH (DE) | 1999-07-21 | — | — | EP | disclosed |
| EP-0661308-B1 | Cyclo-olefin copolymers and process for their preparation | TICONA GMBH (DE) | 1999-06-02 | — | — | EP | disclosed |
| US-5756623-A | MOLDING MATERIALS FOR COMPRESSION MOLDING | HOECHST AG (DE) | 1998-05-26 | — | — | US | disclosed |
| EP-0661310-A2 | Cyclo-olefincopolymers and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-05 | — | — | EP | disclosed |
| EP-0661308-A2 | Cyclo-olefin copolymers and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-05 | — | — | EP | disclosed |