Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.77 |
| ▸ | THRB | P10828 | 2/20 | 0.77 |
| ▸ | RECQL | P46063 | 2/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | HPGD | P15428 | 4/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29395167 | 0.87 | MAPT (0.62) | MAPTTHRBRECQLALDH1A1HPGD | |
| SCHEMBL9226505 | 0.87 | MAPT (0.62) | MAPTTHRBRECQLALDH1A1HPGD | |
| Water SCHEMBL10600149 | 0.86 | MAPT (0.61) | MAPTTHRBRECQLALDH1A1HPGD | |
| SCHEMBL7251971 | 0.82 | MAPT (0.73) | MAPTTHRBRECQLALDH1A1HPGD | |
| SCHEMBL3191317 | 0.81 | MAPT (0.74) | MAPTTHRBRECQLALDH1A1HPGD | |
| SCHEMBL12201210 | 0.77 | KDM4E (0.51) | MAPTTHRBRECQLALDH1A1HPGD | |
| Bromide SCHEMBL3288546 | 0.76 | MAPT (0.68) | MAPTTHRBRECQLALDH1A1HPGD | |
| SCHEMBL7030602 | 0.75 | MAPT (0.50) | MAPTTHRBRECQLALDH1A1HPGD | |
| SCHEMBL8622093 | 0.75 | MAPT (0.49) | MAPTTHRBRECQLALDH1A1HPGD | |
| SCHEMBL7736647 | 0.75 | MEN1 (0.74) | MAPTTHRBRECQLALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648813-B1 | Photographic recording material | AGFA GEVAERT AG (DE) | 1999-04-28 | — | — | EP | disclosed |
| US-5559240-A | METHINE AND THIAZOLE DYES; STORAGE STABILITY; DISCOLORATION INHIBITION | FUJI PHOTO FILM CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |
| EP-0648813-A1 | Photographic recording material | Agfa-Gevaert AG (DE) | 1995-04-19 | — | — | EP | disclosed |
| US-5397693-A | Methine dyes | FUJI PHOTO FILM CO., LTD. (JP) | 1995-03-14 | — | — | US | disclosed |