Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 5/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9312540 | 1.00 | GRM2 (0.37) | GRM2P2RX7SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9312495 | 0.90 | GRM2 (0.39) | GRM2P2RX7SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9312852 | 0.90 | GRM2 (0.48) | GRM2SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL8518042 | 0.90 | GRM2 (0.48) | GRM2SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL8518216 | 0.90 | GRM2 (0.39) | GRM2P2RX7SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8518416 | 0.89 | GRM2 (0.35) | GRM2P2RX7SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8518415 | 0.89 | GRM2 (0.35) | GRM2P2RX7SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8518093 | 0.87 | MAOB (0.39) | GRM2SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL9311883 | 0.87 | MAOB (0.39) | GRM2SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL8517941 | 0.87 | GRM2 (0.36) | GRM2P2RX7SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475273-B1 | Liquid crystal mixture containing halogenated alcenyl compounds | MERCK PATENT GMBH (DE) | 1999-04-07 | — | — | EP | disclosed |
| US-5292452-A | Electrooptical devices; high dielectric anisotropy, low rotation viscosity, short response time | HOFFMANN-LA ROCHE INC. (US) | 1994-03-08 | — | — | US | disclosed |
| EP-0475273-A1 | Halogenated alcenyl compounds | F. HOFFMANN-LA ROCHE AG (CH) | 1992-03-18 | — | — | EP | disclosed |