SCHEMBL8517759

SCHEMBL8517759

C=CCOC(Cl)C=C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28015837 0.77
SCHEMBL6032822 0.77
SCHEMBL24872817 0.72
SCHEMBL9344076 0.72
SCHEMBL8833989 0.72
SCHEMBL7198310 0.72
SCHEMBL2048729 0.71 CA1 (0.32)
SCHEMBL25324243 0.71 CA1 (0.32)
SCHEMBL9389325 0.70
SCHEMBL28123066 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4104456-A Process for the production of poly(allylhalide-allyl alcohol) BLOUNT DAVID H 1978-08-01 US claimed
US-20140066398-A1 HCV POLYMERASE INHIBITORS MEDIVIR, AB (SE) 2014-03-06 US disclosed
WO-2013084165-A1 HCV POLYMERASE INHIBITORS MEDIVIR AB (SE) 2013-06-13 WO disclosed
US-20130143835-A1 HCV Polymerase Inhibitors MEDIVIR AB (SE) 2013-06-06 US disclosed
EP-0767768-B1 HALOALKYLATION PROCESS ALBEMARLE CORP (US) 1999-03-31 EP disclosed
EP-0767768-A1 HALOALKYLATION PROCESS ALBEMARLE CORPORATION (US) 1997-04-16 EP disclosed
EP-0461822-B1 Phosphoric acid-type chelate resin as uranyl ion adsorbent KOREA RES INST CHEM TECH (KR) 1996-05-08 EP disclosed
WO-1996000202-A1 HALOALKYLATION PROCESS ALBEMARLE CORPORATION (US) 1996-01-04 WO disclosed
US-5475170-A Haloalkylation process ALBERMARLE CORPORATION (US) 1995-12-12 US disclosed
US-5319150-A Chloroalkylation of aromatic compounds ALBEMARLE CORPORATION (US) 1994-06-07 US disclosed
US-5136115-A BROMOALKYLATION OF AROMATIC COMPOUNDS ALBERMARLE CORPORATION 1992-08-04 US disclosed
EP-0489804-A1 ASYMMETRIC CHEMICAL SYNTHESIS AND INTERMEDIATES FOR MAKING ANTIFUNGAL COMPOUNDS SCHERING CORPORATION (US) 1992-06-17 EP disclosed
EP-0461822-A2 Phosphoric acid-type chelate resin as uranyl ion adsorbent KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1991-12-18 EP disclosed
EP-0421600-A1 Asymmetric chemical synthesis and intermediates for making antifungal compounds SCHERING CORPORATION (US) 1991-04-10 EP disclosed
WO-1991003451-A1 ASYMMETRIC CHEMICAL SYNTHESIS AND INTERMEDIATES FOR MAKING ANTIFUNGAL COMPOUNDS SCHERING CORPORATION (US) 1991-03-21 WO disclosed
EP-0369728-A1 Haloalkylation of aromatic compounds ETHYL CORPORATION (US) 1990-05-23 EP disclosed
US-4873337-A N-substituted derivatives of 2-(pyridylalkenesulfinyl) benzimidazoles as gastric antisecretory agents THE UPJOHN COMPANY (US) 1989-10-10 US disclosed
EP-0176308-A2 2-(Pyridylalkylenesulfinyl) benzimidazoles THE UPJOHN COMPANY (US) 1986-04-02 EP disclosed
US-4201702-A Process to produce allyl halides copolymers BLOUNT DAVID H 1980-05-06 US disclosed
US-4115635-A Process for the production of poly (allyl halide allyl alcohol) polymer BLOUNT DAVID H 1978-09-19 US disclosed