Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.71 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.62 |
| ▸ | ESR1 | P03372 | 2/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.61 |
| ▸ | TACR2 | P21452 | 2/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.61 |
| ▸ | HTR2A | P28223 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | SHBG | P04278 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.61 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.61 |
| ▸ | HTR2C | P28335 | 1/20 | 0.61 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33437 | 1.00 | KCNH2 (0.71) | KCNH2SIGMAR1ESR1ADRA2AADORA3 | |
| SCHEMBL8679386 | 1.00 | KCNH2 (0.71) | KCNH2SIGMAR1ESR1ADRA2AADORA3 | |
| Benzene SCHEMBL2355019 | 1.00 | KCNH2 (0.71) | KCNH2SIGMAR1ESR1ADRA2AADORA3 | |
| SCHEMBL4932286 | 1.00 | KCNH2 (0.71) | KCNH2SIGMAR1ESR1ADRA2AADORA3 | |
| SCHEMBL8678550 | 1.00 | KCNH2 (0.71) | KCNH2SIGMAR1ESR1ADRA2AADORA3 | |
| Benzene SCHEMBL8518614 | 1.00 | KCNH2 (0.71) | KCNH2SIGMAR1ESR1ADRA2AADORA3 | |
| SCHEMBL1619768 | 1.00 | KCNH2 (0.71) | KCNH2SIGMAR1ESR1ADRA2AADORA3 | |
| SCHEMBL29401 | 1.00 | KCNH2 (0.71) | KCNH2SIGMAR1ESR1ADRA2AADORA3 | |
| SCHEMBL1331102 | 1.00 | KCNH2 (0.71) | KCNH2SIGMAR1ESR1ADRA2AADORA3 | |
| SCHEMBL8614349 | 1.00 | KCNH2 (0.71) | KCNH2SIGMAR1ESR1ADRA2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611119-B1 | Optically active compound, liquid crystal composition containing same, liquid crystal device, display apparatus and display method | CANON KK (JP) | 1999-06-23 | — | — | EP | disclosed |
| US-5830386-A | FLUOROALKYL-SUBSTITUTED PYRIMIDINE | CANON KABUSHIKI KAISHA (JP) | 1998-11-03 | — | — | US | disclosed |
| EP-0611119-A2 | Optically active compound, liquid crystal composition containing same, liquid crystal device, display apparatus and display method | CANON KABUSHIKI KAISHA (JP) | 1994-08-17 | — | — | EP | disclosed |
| EP-0011839-B1 | COUMARIN DERIVATIVES, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 1983-02-16 | — | — | EP | disclosed |
| US-4363812-A | 3-(Tetrazol-5-yl), 4-methyl-8-alkoxy coumarins and anti-allergic compositions thereof | KAKENYAKU KAKO CO., LTD. (JP) | 1982-12-14 | — | — | US | disclosed |
| EP-0011839-A1 | Coumarin derivatives, process for preparing the same and pharmaceutical composition containing the same | Kaken Pharmaceutical Co., Ltd. (JP) | 1980-06-11 | — | — | EP | disclosed |