SCHEMBL8518638

SCHEMBL8518638

CC(C)(C)C[Na].O=C(O)c1cc(C(=O)O)cc(S(=O)(=O)O)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.69
FYN P06241 1/20 0.69
CYP1A2 P05177 1/20 0.43
TPMT P51580 1/20 0.35
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34
HSD17B10 Q99714 1/20 0.34
WDR5 P61964 1/20 0.33
MAPT P10636 1/20 0.33
IL1RN P18510 1/20 0.33
ING2 Q9H160 1/20 0.33
PKM P14618 1/20 0.33
CYP2C19 P33261 1/20 0.33
NR4A1 P22736 1/20 0.33
SMN1; SMN2 Q16637 4/20 0.32
CA12 O43570 2/20 0.32
CA2 P00918 2/20 0.32
CA9 Q16790 2/20 0.32
CA1 P00915 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propane SCHEMBL28160939 0.83 LCK (0.83) LCKFYNCYP1A2TPMTKDM4E
SCHEMBL63440 0.83 LCK (1.00) LCKFYNCYP1A2TPMTKDM4E
SCHEMBL31031074 0.83 LCK (1.00) LCKFYNCYP1A2TPMTKDM4E
SCHEMBL1723587 0.81 LCK (0.87) LCKFYNCYP1A2TPMTKDM4E
Phosphine SCHEMBL1930715 0.81 LCK (0.95) LCKFYNCYP1A2TPMTKDM4E
SCHEMBL10834947 0.81 LCK (0.95) LCKFYNCYP1A2TPMTKDM4E
Ammonia Solution, Strong SCHEMBL1725951 0.81 LCK (0.95) LCKFYNCYP1A2TPMTKDM4E
SCHEMBL144358 0.81 LCK (0.95) LCKFYNCYP1A2TPMTKDM4E
SCHEMBL6292108 0.81 LCK (0.95) LCKFYNCYP1A2TPMTKDM4E
Ammonia Solution, Strong SCHEMBL7022891 0.81 LCK (0.95) LCKFYNCYP1A2TPMTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-11258851-A None JP disclosed