Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST14 | Q9Y5Y6 | 19/20 | 0.49 |
| ▸ | F2 | P00734 | 14/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 11/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 11/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 11/20 | 0.49 |
| ▸ | PLG | P00747 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL852190 | 0.95 | ST14 (0.50) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL851194 | 0.91 | ST14 (0.49) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL851056 | 0.90 | ST14 (0.57) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL851206 | 0.86 | ST14 (0.58) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL851010 | 0.86 | ST14 (0.44) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL851564 | 0.86 | ST14 (0.46) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL852043 | 0.85 | ST14 (0.43) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL852042 | 0.85 | ST14 (0.55) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL851226 | 0.84 | ST14 (0.62) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL851250 | 0.83 | ST14 (0.60) | ST14F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432556-A1 | PROTEASE INHIBITORS | Orion Corporation (FI) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010133748-A1 | PROTEASE INHIBITORS | ORION CORPORATION (FI) | 2010-11-25 | — | — | WO | disclosed |