D-Alanine

D-Alanine

SCHEMBL8518699

C[C@@H](N)C(=O)O.NC(=O)C1CCS1

nearest known ligand 0.33

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.33
CPA1 P15085 1/20 0.32
SLC1A2 P43004 3/20 0.31
SLC1A1 P43005 3/20 0.31
EPHX1 P07099 1/20 0.31
ALOX5 P09917 1/20 0.31
GABRP O00591 2/20 0.30
GABRD O14764 2/20 0.30
GABRA1 P14867 2/20 0.30
GABRB1 P18505 2/20 0.30
GABRG2 P18507 2/20 0.30
GABRB3 P28472 2/20 0.30
GABRA5 P31644 2/20 0.30
GABRA3 P34903 2/20 0.30
GABRA2 P47869 2/20 0.30
GABRB2 P47870 2/20 0.30
GABRA4 P48169 2/20 0.30
GABRE P78334 2/20 0.30
GABRA6 Q16445 2/20 0.30
GABRG1 Q8N1C3 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1260199 0.82
Alanine SCHEMBL27470956 0.72 SLC7A5 (0.56) SLC7A5SLC1A2SLC1A1GABRPGABRD
Alanine SCHEMBL28361274 0.71 SLC7A5 (0.43) SLC7A5SLC1A2SLC1A1
Alanine SCHEMBL2164078 0.71 SLC7A5 (0.43) SLC7A5SLC1A2SLC1A1EPHX1
Alanine SCHEMBL11516934 0.69 SLC7A5 (0.53) SLC7A5SLC1A2SLC1A1GABRPGABRD
Alanine SCHEMBL996400 0.69 SLC7A5 (0.53) SLC7A5SLC1A2SLC1A1GABRPGABRD
Alanine SCHEMBL996694 0.69 SLC7A5 (0.53) SLC7A5SLC1A2SLC1A1GABRPGABRD
Alanine SCHEMBL996399 0.69 SLC7A5 (0.53) SLC7A5SLC1A2SLC1A1GABRPGABRD
Alanine SCHEMBL31 0.69
Alanine SCHEMBL452350 0.69 SLC7A5 (0.59) SLC7A5SLC1A2SLC1A1GABRPGABRD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0811012-B1 METHOD OF PRODUCING L-ASPARTYL-D-ALANINE-N-(THIETHANE-3-YL)-AMIDES DEGUSSA (DE) 1999-05-26 EP claimed