Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7058556 | 1.00 | NPY1R (0.52) | NPY1RSMN1; SMN2MAPTPOLBHTR1A | |
| SCHEMBL7058711 | 0.92 | NPY1R (0.52) | NPY1RSMN1; SMN2MAPTPOLBMEN1 | |
| SCHEMBL7058709 | 0.92 | NPY1R (0.52) | NPY1RSMN1; SMN2MAPTPOLBMEN1 | |
| SCHEMBL7054513 | 0.91 | NPY1R (0.51) | NPY1RSMN1; SMN2MAPTPOLBHTR1A | |
| SCHEMBL7054519 | 0.91 | NPY1R (0.51) | NPY1RSMN1; SMN2MAPTPOLBHTR1A | |
| Hydrochloric Acid SCHEMBL8317459 | 0.84 | MAPT (0.55) | NPY1RSMN1; SMN2MAPTPOLBHTR1A | |
| SCHEMBL7057017 | 0.83 | NPY1R (0.51) | NPY1RSMN1; SMN2MAPTPOLBHTR1A | |
| SCHEMBL7057014 | 0.83 | NPY1R (0.51) | NPY1RSMN1; SMN2MAPTPOLBHTR1A | |
| SCHEMBL7052747 | 0.83 | NPY1R (0.52) | NPY1RMAPTPOLBHTR1ADRD2 | |
| SCHEMBL7056417 | 0.82 | NPY1R (0.54) | NPY1RSMN1; SMN2MAPTPOLBHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918761-A1 | CERTAIN AMIDO- AND AMINO-SUBSTITUTED BENZYLAMINE DERIVATIVES; A NEW CLASS OF NEUROPEPTITE Y1 SPECIFIC LIGANDS | NEUROGEN CORPORATION (US) | 1999-06-02 | — | — | EP | disclosed |
| WO-1998003494-A1 | CERTAIN AMIDO- AND AMINO-SUBSTITUTED BENZYLAMINE DERIVATIVES; A NEW CLASS OF NEUROPEPTITE Y1 SPECIFIC LIGANDS | NEUROGEN CORPORATION (US) | 1998-01-29 | — | — | WO | disclosed |