Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | TP53 | P04637 | 3/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | THRB | P10828 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15304938 | 0.90 | TSHR (0.56) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL7267530 | 0.84 | TSHR (0.62) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL24604357 | 0.84 | TSHR (0.62) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL34872 | 0.83 | TSHR (0.61) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL28785943 | 0.83 | TSHR (0.61) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL27821520 | 0.83 | TSHR (0.61) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL4850587 | 0.83 | TSHR (0.60) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL4843885 | 0.83 | TSHR (0.60) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL12629198 | 0.82 | TSHR (0.57) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL9418348 | 0.82 | TSHR (0.57) | TSHRALDH1A1TP53HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728572-B1 | Process for making transparent articles of graduated refractive index | ESSILOR INT (FR) | 1999-05-19 | — | — | EP | claimed |
| EP-0728572-A2 | Process for making transparent articles of graduated refractive index | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 1996-08-28 | — | — | EP | claimed |
| EP-0250779-A1 | Process for repairing bottles | SOCIETE DES VERNIS BOUVET (FR) | 1988-01-07 | — | — | EP | claimed |
| EP-0728572-B1 | Process for making transparent articles of graduated refractive index | ESSILOR INT (FR) | 1999-05-19 | — | — | EP | disclosed |
| EP-0728572-A2 | Process for making transparent articles of graduated refractive index | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 1996-08-28 | — | — | EP | disclosed |
| EP-0250779-A1 | Process for repairing bottles | SOCIETE DES VERNIS BOUVET (FR) | 1988-01-07 | — | — | EP | disclosed |