Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 4/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8519173 | 1.00 | MEN1 (0.49) | MEN1KMT2ANPBWR1MCHR1ALDH1A1 | |
| SCHEMBL5606338 | 0.86 | KMT2A (0.46) | MEN1KMT2ANPBWR1MCHR1ALDH1A1 | |
| SCHEMBL5606347 | 0.86 | KMT2A (0.46) | MEN1KMT2ANPBWR1MCHR1ALDH1A1 | |
| SCHEMBL5606437 | 0.83 | MEN1 (0.45) | MEN1KMT2ANPBWR1MCHR1ALDH1A1 | |
| SCHEMBL5606438 | 0.83 | MEN1 (0.45) | MEN1KMT2ANPBWR1MCHR1ALDH1A1 | |
| SCHEMBL6431240 | 0.79 | MEN1 (0.45) | MEN1KMT2ANPBWR1MCHR1ALDH1A1 | |
| SCHEMBL6431236 | 0.79 | MEN1 (0.45) | MEN1KMT2ANPBWR1MCHR1ALDH1A1 | |
| SCHEMBL5605947 | 0.78 | MEN1 (0.44) | MEN1KMT2ANPBWR1MCHR1ALDH1A1 | |
| SCHEMBL5605945 | 0.78 | MEN1 (0.44) | MEN1KMT2ANPBWR1MCHR1ALDH1A1 | |
| SCHEMBL5605991 | 0.77 | MEN1 (0.43) | MEN1KMT2ANPBWR1MCHR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929528-A1 | ARALKYL AND ARALKYLIDENE HETEROCYCLIC LACTAMS AND IMIDES | PFIZER INC. (US) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998014433-A1 | ARALKYL AND ARALKYLIDENE HETEROCYCLIC LACTAMS AND IMIDES | PFIZER INC. (US) | 1998-04-09 | — | — | WO | disclosed |