⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1701003 | 0.92 | KDM5A (0.47) | — | |
| SCHEMBL11528780 | 0.90 | KDM5A (0.49) | — | |
| SCHEMBL6253780 | 0.90 | KDM5A (0.49) | — | |
| SCHEMBL6249750 | 0.90 | KDM5A (0.49) | — | |
| SCHEMBL6253808 | 0.90 | KDM5A (0.49) | — | |
| SCHEMBL6253897 | 0.90 | KDM5A (0.49) | — | |
| SCHEMBL629319 | 0.83 | — | — | |
| SCHEMBL11277722 | 0.79 | — | — | |
| SCHEMBL6391364 | 0.77 | — | — | |
| SCHEMBL8815683 | 0.77 | KDM5A (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1456311-B1 | URETHANE POLYMERS THAT REDUCE THE EFFECT OF POLYLACTONE LINKAGES | BASF COATINGS GMBH (DE) | 2012-09-26 | — | — | EP | claimed |
| EP-1456310-B1 | ASYMMETRIC DIISOCYANATE MONOMERS IN URETHANE POLYMERS AND OLIGOMERS TO REDUCE CRYSTALLINITY | BASF CORP (US) | 2008-02-27 | — | — | EP | claimed |
| EP-1453921-B1 | CLEARCOAT COMPOSITION | BASF CORP (US) | 2007-05-09 | — | — | EP | claimed |
| CN-114478303-A | Method for synthesizing carbidopa | 浙江野风药业股份有限公司 | 2022-05-13 | — | — | CN | disclosed |
| EP-3313831-A1 | N-SUBSTITUTED HYDROXAMIC ACIDS WITH CARBON-BASED LEAVING GROUPS AS EFFICIENT HNO DONORS AND USES THEREOF | The Johns Hopkins University (US) | 2018-05-02 | — | — | EP | disclosed |
| WO-2016210392-A1 | N-SUBSTITUTED HYDROXAMIC ACIDS WITH CARBON-BASED LEAVING GROUPS AS EFFICIENT HNO DONORS AND USES THEREOF | THE JOHNS HOPKINS UNIVERSITY (US) | 2016-12-29 | — | — | WO | disclosed |
| EP-2432811-B1 | CURABLE COATING COMPOSITION CONTAINING A COMPOUND HAVING A URETDIONE GROUP AND A DIFFERENT FUNCTIONAL GROUP AND CURED COATINGS | BASF COATINGS GMBH (DE) | 2016-03-23 | — | — | EP | disclosed |
| US-8629231-B2 | Methods of making oligomers, coating compositions containing them, and coated articles | BASF COATINGS GMBH (DE) | 2014-01-14 | — | — | US | disclosed |
| US-8487108-B2 | Piperidinyl carbamate intermediates for the synthesis of aspartic protease inhibitors | VITAE PHARMACEUTICALS, INC. (US) | 2013-07-16 | — | — | US | disclosed |
| US-8455497-B2 | Inhibitors of aspartyl protease | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2013-06-04 | — | — | US | disclosed |
| EP-2432844-B1 | OLIGOMERS HAVING URETDIONE STRUCTURE, METHODS OF MAKING THEM, COATING COMPOSITIONS CONTAINING THEM, AND CURED COATINGS THEREOF | BASF COATINGS GMBH (DE) | 2013-03-20 | — | — | EP | disclosed |
| US-20090275581-A1 | RENIN INHIBITORS | VITAE PHARMACEUTICALS, INC. | 2009-11-05 | — | — | US | disclosed |
| US-20090274650-A1 | INHIBITORS OF ASPARTYL PROTEASE | VERTEX PHARMACEUTICALS INCORPORATED | 2009-11-05 | — | — | US | disclosed |
| US-20090264428-A1 | Renin Inhibitors | VITAE PHARMACEUTICALS, INC. | 2009-10-22 | — | — | US | disclosed |
| US-20090186884-A1 | such as N-(3-amino-2-hydroxypropyl)-3-(1-(2-(2-ethylphenoxy)phenyl)-1-hydroxy-5-;methoxypentyl)piperidine-1-carboxamide, used for the treatment of cardiovascular disorders | VITAE PHARMACEUTICALS, INC. | 2009-07-23 | — | — | US | disclosed |
| WO-2008124575-A1 | RENIN INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-10-16 | — | — | WO | disclosed |
| WO-2008124582-A1 | RENIN INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-10-16 | — | — | WO | disclosed |
| WO-2005047234-A1 | METHOD FOR PRODUCING CARBAMATE GROUP-CONTAINING (METH)ACRYLIC ESTERS | Röhm GmbH & Co. KG (DE) | 2005-05-26 | — | — | WO | disclosed |
| US-4331438-A | TREATMENT WITH A FORMALDEHYDE ACCEPTOR | BASF WYANDOTTE CORPORATION (US) | 1982-05-25 | — | — | US | disclosed |
| US-4160077-A | Process of crosslinking unsaturated hydrocarbon polymers employing novel carbamates | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-07-03 | — | — | US | disclosed |