⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11703774 | 0.86 | — | — | |
| SCHEMBL4576011 | 0.84 | — | — | |
| SCHEMBL7094163 | 0.83 | — | — | |
| SCHEMBL352688 | 0.82 | — | — | |
| SCHEMBL387055 | 0.79 | — | — | |
| SCHEMBL3692284 | 0.79 | PRKD3 (0.35) | — | |
| SCHEMBL364845 | 0.78 | — | — | |
| SCHEMBL11184029 | 0.78 | — | — | |
| SCHEMBL28230241 | 0.77 | PRKD3 (0.38) | — | |
| SCHEMBL23706757 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3280402-B1 | TOLAN COMPOUNDS FOR PROMOTING WOUND HEALING | BIOMENDICS LLC (US) | 2024-06-05 | — | — | EP | disclosed |
| CN-107847466-B | Formulations and methods for modulating wound healing | 贝欧曼蒂克丝公司 | 2024-02-06 | — | — | CN | disclosed |
| US-11786481-B2 | Formulation and process for modulating wound healing | BioMendics, LLC (US) | 2023-10-17 | — | — | US | disclosed |
| US-20230130617-A1 | PROCESS FOR IMPROVED OPIOID SYNTHESIS | RHODES TECHNOLOGIES (US) | 2023-04-27 | — | — | US | disclosed |
| US-20220296538-A1 | Substituted Tolans for the Modulation of Microbial Colonization | BioMendics, LLC (US) | 2022-09-22 | — | — | US | disclosed |
| US-11351126-B2 | Substituted tolans for the modulation of microbial colonization | BioMendics, LLC (US) | 2022-06-07 | — | — | US | disclosed |
| US-20210228501-A1 | Formulation and Process for Modulating Wound Healing | BioMendics, LLC (US) | 2021-07-29 | — | — | US | disclosed |
| CN-111526873-A | Substituted tolanes for regulating microbial colonization | 生物曼迪克斯有限责任公司 | 2020-08-11 | — | — | CN | disclosed |
| US-20200206154-A1 | Substituted Tolans for the Modulation of Microbial Colonization | BioMendics, LLC (US) | 2020-07-02 | — | — | US | disclosed |
| EP-2880033-B1 | CYCLIC UREA- OR LACTAM-SUBSTITUTED QUINOXALINE-TYPE PIPERIDINE COMPOUNDS AND THE USES THEREOF | PURDUE PHARMA LP (US) | 2020-06-17 | — | — | EP | disclosed |
| WO-2011103932-A1 | A PROCESS FOR THE PREPARATION OF SUBSTITUTED PROLYL PEPTIDES AND SIMILAR PEPTIDOMIMETICS | VERENIGING VOOR CHRISTELIJK HOGER ONDERWIJS, WETENSCHAPPELIJK ONDERZOEK EN PATIËNTENZORG (NL) | 2011-09-01 | — | — | WO | disclosed |
| EP-2307419-A2 | BIOCATALYTIC PROCESSES FOR THE PREPARATION OF SUBSTANTIALLY STEREOMERICALLY PURE FUSED BICYCLIC PROLINE COMPOUNDS | Codexis, Inc. (US) | 2011-04-13 | — | — | EP | disclosed |
| US-20100324080-A1 | Benzomorphan Compounds | PURDUE PHARMA L.P. (US) | 2010-12-23 | — | — | US | disclosed |
| EP-2225246-A1 | BENZOMORPHAN COMPOUNDS | Purdue Pharma LP (US) | 2010-09-08 | — | — | EP | disclosed |
| US-20100216726-A1 | Substituted-Quinoxaline-Type Piperidine Compounds and the Uses Thereof | PURDUE PHARMA L.P. (US) | 2010-08-26 | — | — | US | disclosed |
| US-20100063300-A1 | BIOCATALYTIC PROCESSES FOR THE PREPARATION OF SUBSTANTIALLY STEREOMERICALLY PURE FUSED BICYCLIC PROLINE COMPOUNDS | CODEXIS, INC. (US) | 2010-03-11 | — | — | US | disclosed |
| WO-2010008828-A2 | BIOCATALYTIC PROCESSES FOR THE PREPARATION OF SUBSTANTIALLY STEREOMERICALLY PURE FUSED BICYCLIC PROLINE COMPOUNDS | CODEXIS, INC. (US) | 2010-01-21 | — | — | WO | disclosed |
| EP-2086958-A2 | SUBSTITUTED-QUINOXALINE-TYPE-PIPERIDINE COMPOUNDS AND THE USES THEREOF | Purdue Pharma LP (US) | 2009-08-12 | — | — | EP | disclosed |
| WO-2009068989-A1 | BENZOMORPHAN COMPOUNDS | PURDUE PHARMA L.P. (DE) | 2009-06-04 | — | — | WO | disclosed |
| WO-2009027820-A2 | SUBSTITUTED-QUINOXALINE-TYPE-PIPERIDINE COMPOUNDS AND THE USES THEREOF | PURDUE PHARMA L.P. (DE) | 2009-03-05 | — | — | WO | disclosed |