Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 17/20 | 0.62 |
| ▸ | FNTB | P49356 | 17/20 | 0.62 |
| ▸ | PGGT1B | P53609 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26818366 | 0.87 | FNTA (0.68) | FNTAFNTBPGGT1B | |
| SCHEMBL13138431 | 0.87 | FNTA (0.68) | FNTAFNTBPGGT1B | |
| SCHEMBL34473997 | 0.79 | FNTA (0.58) | FNTAFNTBPGGT1BLMNA | |
| SCHEMBL30051582 | 0.79 | FNTA (0.58) | FNTAFNTBPGGT1BLMNA | |
| SCHEMBL2543348 | 0.79 | FNTA (0.67) | FNTAFNTBPGGT1B | |
| SCHEMBL27799999 | 0.79 | FNTA (0.67) | FNTAFNTBPGGT1B | |
| SCHEMBL29454463 | 0.77 | FNTA (0.42) | FNTAFNTBPGGT1B | |
| SCHEMBL29359191 | 0.77 | FNTA (0.64) | FNTAFNTBPGGT1B | |
| SCHEMBL26818348 | 0.77 | FNTA (0.69) | FNTAFNTBPGGT1B | |
| SCHEMBL8519036 | 0.77 | FNTA (0.78) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998009641-A1 | SEMIPEPTOID FARNESYL PROTEIN TRANSFERASE INHIBITORS AND ANALOGS THEREOF | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 1998-03-12 | — | — | WO | claimed |
| US-5990277-A | ANTICARCINOGENIC/ANTITUMOR/ANTIPROLIFERATIVE AGENTS AGAINST ONCOGENIC OR NON-ONCOGENIC RAS ASSOCIATED CANCERS AND PROLIFERATIVE DISORDERS; DERIVED FROM UNIVERSAL RECOGNITION TETRAPEPTIDE SEQUENCE CAAX | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HERBREW UNIVERSITY OF JERUSALEM (IL) | 1999-11-23 | — | — | US | disclosed |
| WO-1998009641-A1 | SEMIPEPTOID FARNESYL PROTEIN TRANSFERASE INHIBITORS AND ANALOGS THEREOF | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 1998-03-12 | — | — | WO | disclosed |