Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8519937 | 1.00 | HIF1A (0.46) | HIF1AL3MBTL1LMNATP53HTT | |
| SCHEMBL8400229 | 0.89 | HIF1A (0.47) | HIF1AL3MBTL1LMNATP53HTT | |
| SCHEMBL8400225 | 0.89 | HIF1A (0.47) | HIF1AL3MBTL1LMNATP53HTT | |
| SCHEMBL8398729 | 0.88 | HIF1A (0.50) | HIF1AL3MBTL1TP53HTTKMT2A | |
| SCHEMBL8398720 | 0.88 | HIF1A (0.50) | HIF1AL3MBTL1TP53HTTKMT2A | |
| SCHEMBL8395411 | 0.86 | HIF1A (0.48) | HIF1ATP53HTTALDH1A1 | |
| SCHEMBL8395405 | 0.86 | HIF1A (0.48) | HIF1ATP53HTTALDH1A1 | |
| SCHEMBL8396240 | 0.86 | HIF1A (0.48) | HIF1ATP53HTT | |
| SCHEMBL8396228 | 0.86 | HIF1A (0.48) | HIF1ATP53HTT | |
| SCHEMBL8624002 | 0.85 | HIF1A (0.48) | HIF1AL3MBTL1TP53HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644183-B1 | Process of producing N-alkylacetamides | SHIONOGI & CO (JP) | 1999-06-02 | — | — | EP | disclosed |
| US-5498792-A | Process of producing N-alkylacetamides | SHIONOGI & CO., LTD. (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0644183-A2 | Process of producing N-alkylacetamides | SHIONOGI & CO., LTD. (JP) | 1995-03-22 | — | — | EP | disclosed |