Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | REN | P00797 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PEPD | P12955 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11605557 | 1.00 | ACE (0.43) | ACEKDM4EF2RENLMNA | |
| SCHEMBL11605553 | 1.00 | ACE (0.43) | ACEKDM4EF2RENLMNA | |
| SCHEMBL8396582 | 0.84 | DPP4 (0.38) | — | |
| SCHEMBL30040159 | 0.82 | DPP4 (0.36) | — | |
| SCHEMBL11605320 | 0.80 | ACE (0.40) | ACE | |
| Hydrochloric Acid SCHEMBL5570670 | 0.76 | ACE (0.39) | ACEKDM4EF2RENLMNA | |
| Hydrochloric Acid SCHEMBL5569215 | 0.76 | ACE (0.39) | ACEKDM4EF2RENLMNA | |
| SCHEMBL4326048 | 0.74 | ACE (0.36) | ACE | |
| SCHEMBL11603642 | 0.74 | ACE (0.36) | ACE | |
| SCHEMBL2451197 | 0.74 | FFAR3 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0491061-B1 | Use of N-(aminoacyl)-amino acids for preparing dopaminergic and gonadotropic medicaments. | WETH GOSBERT DR MED DR RER NAT (DE) | 1999-06-09 | — | — | EP | claimed |
| EP-0498899-B1 | Use of N-(mercaptoacyl)-amino acids as dopaminergic und gonadoptropic medicaments | WETH GOSBERT DR MED DR RER NAT (DE) | 1998-10-07 | — | — | EP | claimed |
| EP-0498899-A1 | Use of N-(mercaptoacyl)-amino acids as dopaminergic und gonadoptropic medicaments | Weth, Gosbert Dr. med., Dr. rer. nat. (DE) | 1992-08-19 | — | — | EP | claimed |
| EP-0498899-B1 | Use of N-(mercaptoacyl)-amino acids as dopaminergic und gonadoptropic medicaments | WETH GOSBERT DR MED DR RER NAT (DE) | 1998-10-07 | — | — | EP | disclosed |
| EP-0498899-A1 | Use of N-(mercaptoacyl)-amino acids as dopaminergic und gonadoptropic medicaments | Weth, Gosbert Dr. med., Dr. rer. nat. (DE) | 1992-08-19 | — | — | EP | disclosed |
| EP-0498899-A1 | Use of N-(mercaptoacyl)-amino acids as dopaminergic und gonadoptropic medicaments | Weth, Gosbert Dr. med., Dr. rer. nat. (DE) | 1992-08-19 | — | — | EP | disclosed |