Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPFFR1 | Q9GZQ6 | 11/20 | 0.63 |
| ▸ | NPFFR2 | Q9Y5X5 | 11/20 | 0.63 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.54 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | CCR3 | P51677 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3167579 | 0.86 | NPFFR1 (0.60) | NPFFR1NPFFR2OPRK1OPRL1CYP3A4 | |
| Hydrochloric Acid SCHEMBL11565355 | 0.85 | NPFFR1 (0.58) | NPFFR1NPFFR2OPRK1OPRL1POLB | |
| SCHEMBL3178014 | 0.84 | NPFFR1 (0.67) | NPFFR1NPFFR2OPRK1OPRL1POLB | |
| Hydrochloric Acid SCHEMBL6123389 | 0.84 | NPFFR1 (0.67) | NPFFR1NPFFR2OPRK1OPRL1POLB | |
| SCHEMBL8526584 | 0.84 | NPFFR1 (0.57) | NPFFR1NPFFR2OPRK1OPRL1CYP3A4 | |
| SCHEMBL7953417 | 0.84 | NPFFR1 (0.57) | NPFFR1NPFFR2OPRK1OPRL1CYP3A4 | |
| SCHEMBL13525518 | 0.83 | NPFFR1 (0.56) | NPFFR1NPFFR2OPRK1OPRL1CYP3A4 | |
| Hydrochloric Acid SCHEMBL11564470 | 0.83 | NPFFR1 (0.56) | NPFFR1NPFFR2OPRK1OPRL1POLB | |
| SCHEMBL11566119 | 0.82 | NPFFR1 (0.55) | NPFFR1NPFFR2OPRK1OPRL1CYP3A4 | |
| Hydrochloric Acid SCHEMBL11569017 | 0.81 | NPFFR1 (0.54) | NPFFR1NPFFR2OPRK1OPRL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2455377-A1 | Synthesis of fentanyl analogs | hameln rds gmbh (DE) | 2012-05-23 | — | — | EP | disclosed |