SCHEMBL8520107

SCHEMBL8520107

C=CCOC(=O)/C=C(/CCCS(=O)(=O)O)C(=O)OCC=C

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
MAPT P10636 1/20 0.33
CACNA1B Q00975 1/20 0.33
APBA1 Q02410 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8520112 0.88 TSHR (0.33) TSHR
SCHEMBL850326 0.87 TSHR (0.33) TSHR
SCHEMBL1414788 0.87 TSHR (0.33) TSHR
SCHEMBL1414790 0.86 TSHR (0.32) TSHR
SCHEMBL11333154 0.78 TSHR (0.59) TSHR
SCHEMBL11333210 0.78 TSHR (0.59) TSHR
SCHEMBL2938493 0.74 MAPT (0.41) TSHRMAPTCACNA1BAPBA1
SCHEMBL2936821 0.74 MAPT (0.41) TSHRMAPTCACNA1BAPBA1
SCHEMBL2936820 0.74 MAPT (0.41) TSHRMAPTCACNA1BAPBA1
SCHEMBL23639581 0.71 MAPT (0.42) TSHRMAPTCACNA1BAPBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5898043-A CONSISTS OF A FILM FORMING RESIN AND A CROSSLINKING AGENT CAPABLE OF FORMING CROSSLINKED RESIN POWDER HAS A SPECIFIC VOLUME-AVERAGE PARTICLE DIAMETER AND SHAPE FACTOR 100.5 TO 160 NIPPON CARBIDE KOGYO KABUSHIKI KAISHA (JP) 1999-04-27 US disclosed
EP-0751192-A1 POWDER PAINT, METHOD OF MANUFACTURING THE SAME, AND METHOD OF PAINTING USING THE PAINT NIPPON CARBIDE KOGYO KABUSHIKI KAISHA (JP) 1997-01-02 EP disclosed