Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL872855 | 0.80 | — | — | |
| SCHEMBL12657856 | 0.80 | — | — | |
| SCHEMBL5936289 | 0.79 | PIK3CD (0.34) | CYP2A6CHRM2CHRM3CHRM4CHRM5 | |
| SCHEMBL19744382 | 0.74 | — | — | |
| SCHEMBL4454343 | 0.73 | — | — | |
| SCHEMBL12302762 | 0.73 | — | — | |
| SCHEMBL17548907 | 0.73 | PIK3CD (0.32) | — | |
| SCHEMBL16384646 | 0.70 | — | — | |
| SCHEMBL14316683 | 0.69 | CHRM2 (0.38) | CYP2A6CHRM2CHRM3CHRM4CHRM5 | |
| SCHEMBL16312550 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5989842-A | OXIDIZING WITH PERIODATE; CROSSLINKING WITH DIAMINOOXAALKANE; COUPLING BIOMOLECULE | BIO-TEZ BERLIN-BUCH GMBH (DE) | 1999-11-23 | — | — | US | claimed |
| US-5989842-A | OXIDIZING WITH PERIODATE; CROSSLINKING WITH DIAMINOOXAALKANE; COUPLING BIOMOLECULE | BIO-TEZ BERLIN-BUCH GMBH (DE) | 1999-11-23 | — | — | US | disclosed |