Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | GABRP | O00591 | 3/20 | 0.44 |
| ▸ | GABRD | O14764 | 3/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.44 |
| ▸ | GABRE | P78334 | 3/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.44 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17861173 | 0.80 | ATM (0.45) | MAPTKDM4ESIRT2SIRT1MEN1 | |
| SCHEMBL19924468 | 0.76 | CA12 (0.41) | LMNAMAPTKDM4ESIRT2SIRT1 | |
| SCHEMBL7010672 | 0.76 | SIRT2 (0.48) | LMNAMAPTKDM4ESIRT2SIRT1 | |
| SCHEMBL23119726 | 0.76 | HSP90AA1 (0.56) | HSP90AA1LMNAMAPTAURKAKDM4E | |
| SCHEMBL7011009 | 0.75 | SIRT2 (0.47) | LMNAMAPTKDM4ESIRT2SIRT1 | |
| SCHEMBL22062844 | 0.75 | HSP90AA1 (0.55) | HSP90AA1LMNAMAPTAURKAKDM4E | |
| SCHEMBL12610020 | 0.75 | HSP90AA1 (0.55) | HSP90AA1LMNAMAPTAURKAKDM4E | |
| SCHEMBL9119078 | 0.75 | HSP90AA1 (0.72) | HSP90AA1LMNAMAPTAURKAKDM4E | |
| SCHEMBL9119821 | 0.75 | HSP90AA1 (0.55) | HSP90AA1LMNAMAPTAURKAKDM4E | |
| SCHEMBL29589834 | 0.75 | HSP90AA1 (0.55) | HSP90AA1LMNAMAPTAURKAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927192-A1 | MODIFIED AMINOACIDS, PHARMACEUTICALS CONTAINING THESE COMPOUNDS AND METHOD FOR THEIR PRODUCTION | Dr. Karl Thomae GmbH (DE) | 1999-07-07 | — | — | EP | claimed |
| WO-1998011128-A1 | MODIFIED AMINOACIDS, PHARMACEUTICALS CONTAINING THESE COMPOUNDS AND METHOD FOR THEIR PRODUCTION | DR. KARL THOMAE GMBH (DE) | 1998-03-19 | — | — | WO | claimed |