Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.44 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.40 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.40 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.40 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10744944 | 0.98 | USP2 (0.65) | USP2SPHK1HTTMEN1THRB | |
| SCHEMBL15561419 | 0.98 | USP2 (0.65) | USP2SPHK1HTTMEN1THRB | |
| SCHEMBL27256923 | 0.98 | USP2 (0.65) | USP2SPHK1HTTMEN1THRB | |
| SCHEMBL9058998 | 0.98 | USP2 (0.65) | USP2SPHK1HTTMEN1THRB | |
| SCHEMBL4621760 | 0.98 | USP2 (0.65) | USP2SPHK1HTTMEN1THRB | |
| SCHEMBL4732060 | 0.98 | USP2 (0.65) | USP2SPHK1HTTMEN1THRB | |
| SCHEMBL8521337 | 0.96 | USP2 (0.61) | USP2SPHK1HTTMEN1THRB | |
| SCHEMBL27074550 | 0.94 | USP2 (0.65) | USP2SPHK1HTTMEN1THRB | |
| SCHEMBL10745408 | 0.94 | USP2 (0.53) | USP2SPHK1HTTMEN1THRB | |
| SCHEMBL19542184 | 0.94 | USP2 (0.53) | USP2SPHK1HTTMEN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948389-A | Method of enhancing the analgesic efficacy of locally and topically administered opioids and other local anesthetics | EL KHOURY & STEIN, LTD. (US) | 1999-09-07 | — | — | US | disclosed |