⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propene SCHEMBL3221397 | 0.94 | — | — | |
| Propene SCHEMBL11497881 | 0.94 | — | — | |
| Propene SCHEMBL4460784 | 0.94 | — | — | |
| Propene SCHEMBL8039600 | 0.87 | TSHR (0.33) | — | |
| Propene SCHEMBL4948068 | 0.87 | TSHR (0.33) | — | |
| Propene SCHEMBL30536989 | 0.87 | — | — | |
| Propene SCHEMBL8190454 | 0.87 | TSHR (0.33) | — | |
| Propene SCHEMBL8431129 | 0.87 | TSHR (0.33) | — | |
| Propene SCHEMBL342422 | 0.87 | — | — | |
| Propene SCHEMBL193 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880113-A | ANTIPROLIFERATIVE AGENTS, CELL DIFFERENTIATION INDUCERS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1999-03-09 | — | — | US | disclosed |
| EP-0474517-B1 | Novel use of 1alpha-hydroxylated-19-nor-vitamin D compounds to treat psoriasis | WISCONSIN ALUMNI RES FOUND (US) | 1998-11-18 | — | — | EP | disclosed |
| US-5710294-A | TREATMENT OF MALIGNANT AND OTHER DISEASES CHARACTERIZED BY PROLIFERATIVE GROWTH OF UNDIFFERENTIATED CELLS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1998-01-20 | — | — | US | disclosed |
| US-5654292-A | TREATING SKIN DISORDERS USING VITAMIN D3 DERIVATIVES; SIDE EFFECT REDUCTION | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1997-08-05 | — | — | US | disclosed |
| US-5633241-A | ADMINISTERING AS ANTILEUKEMIA AGENT | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1997-05-27 | — | — | US | disclosed |
| US-5618805-A | 19-nor-vitamin D compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1997-04-08 | — | — | US | disclosed |
| US-5612326-A | ADMINISTERING VITAMIN D COMPOUNDS BY MOUTH OR INJECTION | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1997-03-18 | — | — | US | disclosed |
| US-5587497-A | CONTROLLING CELL DIFFERENTIATION | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1996-12-24 | — | — | US | disclosed |
| US-5578587-A | Methods and compositions containing vitamin D compounds for improvement of skin conditions | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1996-11-26 | — | — | US | disclosed |
| US-5561123-A | ANTITUMOR AGENTS, ANTICARCINOGENIC AGENT | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1996-10-01 | — | — | US | disclosed |
| EP-0387077-B1 | 19-Nor vitamin D compounds | WISCONSIN ALUMNI RES FOUND (US) | 1994-01-19 | — | — | EP | disclosed |
| US-5246925-A | 19-nor-vitamin D compounds for use in treating hyperparathyroidism | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1993-09-21 | — | — | US | disclosed |
| US-5237110-A | Differentiation of malignant cells, stopping proliferation of undifferentiated skin cells | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1993-08-17 | — | — | US | disclosed |
| US-5185150-A | Treating skin disorders such as dryness, wrinkles, slackness, topical lotion, cream | WISCONSIN ALUMNI RESEARCH FDN. (US) | 1993-02-09 | — | — | US | disclosed |
| EP-0480572-A1 | Use of vitamin D compounds for the manufacture of a cosmetic composition and use of it for improvements of skin conditions | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1992-04-15 | — | — | EP | disclosed |
| EP-0474517-A2 | Novel use of 1alpha-hydroxylated-19-nor-vitamin D compounds to treat psoriasis | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1992-03-11 | — | — | EP | disclosed |
| EP-0443021-A1 | NOVEL USE OF VITAMIN D COMPOUNDS TO INHIBIT REPLICATION OF THE AIDS VIRUS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1991-08-28 | — | — | EP | disclosed |
| WO-1991003246-A1 | NOVEL USE OF VITAMIN D COMPOUNDS TO INHIBIT REPLICATION OF THE AIDS VIRUS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1991-03-21 | — | — | WO | disclosed |
| WO-1990010620-A1 | 19-NOR-VITAMIN D COMPOUNDS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1990-09-20 | — | — | WO | disclosed |
| EP-0387077-A1 | 19-Nor vitamin D compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1990-09-12 | — | — | EP | disclosed |