Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 17/20 | 0.53 |
| ▸ | YES1 | P07947 | 2/20 | 0.52 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8520942 | 1.00 | SRC (0.53) | SRCYES1KLKB1CTSDPARP15 | |
| SCHEMBL8419343 | 0.80 | SRC (0.59) | SRCYES1PARP15PARP10 | |
| SCHEMBL8809924 | 0.79 | SRC (0.62) | SRCYES1 | |
| SCHEMBL8421353 | 0.74 | SRC (0.61) | SRCYES1PARP15PARP10 | |
| SCHEMBL7653013 | 0.73 | SRC (0.82) | SRCYES1PARP15PARP10 | |
| SCHEMBL7653010 | 0.73 | SRC (0.82) | SRCYES1PARP15PARP10 | |
| SCHEMBL7653006 | 0.73 | SRC (0.82) | SRCYES1PARP15PARP10 | |
| SCHEMBL7654913 | 0.73 | SRC (0.82) | SRCYES1PARP15PARP10 | |
| SCHEMBL14582815 | 0.71 | SRC (0.54) | SRCYES1PARP15PARP10 | |
| SCHEMBL8419506 | 0.69 | SRC (0.85) | SRCYES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922697-A | Compounds, compositions and methods for inhibiting the binding of proteins containing an SH2 domain to cognate phosphorylated proteins | WARNER-LAMBERT COMPANY (US) | 1999-07-13 | — | — | US | disclosed |