Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 7/20 | 0.69 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2187939 | 0.86 | SLC18A3 (0.76) | SLC18A3SIGMAR1CYP2D6CYP1A2 | |
| SCHEMBL2187946 | 0.86 | SLC18A3 (0.76) | SLC18A3SIGMAR1CYP2D6CYP1A2 | |
| SCHEMBL2187943 | 0.86 | SLC18A3 (0.76) | SLC18A3SIGMAR1CYP2D6CYP1A2 | |
| SCHEMBL2191623 | 0.85 | SLC18A3 (0.74) | SLC18A3SIGMAR1 | |
| SCHEMBL2191616 | 0.85 | SLC18A3 (0.74) | SLC18A3SIGMAR1 | |
| SCHEMBL2191620 | 0.85 | SLC18A3 (0.74) | SLC18A3SIGMAR1 | |
| SCHEMBL8435485 | 0.82 | SLC18A3 (0.79) | SLC18A3SIGMAR1 | |
| SCHEMBL6023725 | 0.81 | MEN1 (0.68) | SLC18A3SIGMAR1CYP2D6CYP1A2TSHR | |
| SCHEMBL22755777 | 0.81 | MEN1 (0.68) | SLC18A3SIGMAR1CYP2D6CYP1A2TSHR | |
| SCHEMBL3598146 | 0.81 | MEN1 (0.68) | SLC18A3SIGMAR1CYP2D6CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5876694-A | NON-INVASIVELY MAPPING CHOLINERGIC INNERVATION IN A LIVING BRAIN COMPRISES INJECTING THE BRAIN WITH A RADIOLABELLED VESAMICOL DERIVATIVE, MAGNETIC RESONANCE IMAGING | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1999-03-02 | — | — | US | disclosed |
| US-5789420-A | Azavesamicols | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1998-08-04 | — | — | US | disclosed |
| EP-0643696-A1 | AZAVESAMICOLS | THE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1995-03-22 | — | — | EP | disclosed |
| EP-0643696-A4 | AZAVESAMICOLS. | UNIV MINNESOTA (US) | 1995-01-20 | — | — | EP | disclosed |
| US-5338852-A | Azavesamicols | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1994-08-16 | — | — | US | disclosed |
| WO-1993024457-A1 | AZAVESAMICOLS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1993-12-09 | — | — | WO | disclosed |