Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 8/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.49 |
| ▸ | CYP3A5 | P20815 | 5/20 | 0.49 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6090239 | 0.81 | CYP19A1 (0.49) | CYP19A1CYP3A4CYP3A5KCNA5CYP1A2 | |
| SCHEMBL28206645 | 0.78 | CYP19A1 (0.58) | CYP19A1CYP3A4CYP3A5KCNA5CYP1A2 | |
| SCHEMBL1614645 | 0.78 | CYP3A4 (0.47) | CYP19A1CYP3A4CYP3A5KCNA5CYP1A2 | |
| SCHEMBL4981210 | 0.78 | CYP19A1 (0.59) | CYP19A1CYP3A4CYP3A5KCNA5CYP1A2 | |
| SCHEMBL8362586 | 0.76 | TSHR (0.52) | CYP3A4CYP1A2CYP2C9CYP2C19LMNA | |
| Hydrochloric Acid SCHEMBL10578749 | 0.76 | CYP19A1 (0.57) | CYP19A1CYP3A4CYP3A5KCNA5CYP1A2 | |
| SCHEMBL17963323 | 0.75 | CYP3A4 (0.46) | CYP19A1CYP3A4CYP3A5KCNA5CYP1A2 | |
| SCHEMBL11628920 | 0.75 | CYP19A1 (0.64) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL27609994 | 0.75 | CYP19A1 (0.55) | CYP19A1CYP3A4CYP3A5KCNA5CYP1A2 | |
| SCHEMBL19627972 | 0.73 | CYP19A1 (0.57) | CYP19A1CYP3A4CYP3A5KCNA5CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901490-A1 | BICYCLIC AMINES AS INSECTICIDES | ZENECA LIMITED (GB) | 1999-03-17 | — | — | EP | disclosed |
| WO-1997043286-A1 | BICYCLIC AMINES AS INSECTICIDES | ZENECA LIMITED (GB) | 1997-11-20 | — | — | WO | disclosed |