SCHEMBL852228

SCHEMBL852228

C1=CC=CC(C2=CCCCCCCC2)=CC=C1

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TYMP P19971 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
ALDH1A1 P00352 1/20 0.30
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1828273 1.00 TYMP (0.31) TYMPTDP1ALDH1A1CYP3A4
SCHEMBL122933 0.82
SCHEMBL11693170 0.78
SCHEMBL5567656 0.75
SCHEMBL2105114 0.72 TYMP (0.41) TYMPTDP1ALDH1A1CYP3A4
SCHEMBL18244171 0.72 TYMP (0.41) TYMPTDP1ALDH1A1CYP3A4
SCHEMBL3502363 0.72 TYMP (0.41) TYMPTDP1ALDH1A1CYP3A4
SCHEMBL21057468 0.72 TYMP (0.41) TYMPTDP1ALDH1A1CYP3A4
SCHEMBL3233362 0.72 TYMP (0.41) TYMPTDP1ALDH1A1CYP3A4
SCHEMBL18244172 0.72 TYMP (0.41) TYMPTDP1ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3294747-B1 RUTHENIUM COMPLEXES, METHOD OF PRODUCING THEM, AND THEIR USE UNIV WARSZAWSKI (PL) 2021-02-24 EP disclosed
EP-3548501-B1 NOVEL RUTHENIUM COMPLEX, METHOD OF ITS PRODUCTION AND ITS USE IN REACTION OF OLEFINE METATHESIS UNIV WARSZAWSKI (PL) 2021-02-17 EP disclosed
EP-3564240-A1 PIPERIDINE INTERMEDIATES Purdue Pharma L.P. (US) 2019-11-06 EP disclosed
EP-3548501-A1 NOVEL RUTHENIUM COMPLEX, METHOD OF ITS PRODUCTION AND ITS USE IN REACTION OF OLEFINE METATHESIS Uniwersytet Warszawski (PL) 2019-10-09 EP disclosed
WO-2018100515-A1 NOVEL RUTHENIUM COMPLEX, METHOD OF ITS PRODUCTION AND ITS USE IN REACTION OF OLEFINE METATHESIS UNIWERSYTET WARSZAWSKI (PL) 2018-06-07 WO disclosed
EP-3294747-A1 RUTHENIUM COMPLEXES, METHOD OF PRODUCING THEM, AND THEIR USE Uniwersytet Warszawski (PL) 2018-03-21 EP disclosed
EP-3153161-A1 SMALL MOLECULE INHIBITORS OF TRPA1 B.R.A.I.N. Biotechnology Research And Information Network AG (DE) 2017-04-12 EP disclosed
US-9585865-B2 Small molecule modulators of the cold and menthol receptor TRPM8 B.R.A.I.N. BIOTECHNOLOGY RESEARCH AND INFORMATION NETWORK AG (DE) 2017-03-07 US disclosed
EP-2706995-B1 SMALL MOLECULE INHIBITORS OF TRPA1 BRAIN BIOTECHNOLOGY RES & INFORMATION NETWORK AG (DE) 2016-11-30 EP disclosed
EP-2654751-B1 PHOSPHORUS-SUBSTITUTED QUINOXALINE-TYPE PIPERIDINE COMPOUNDS AND USES THEREOF PURDUE PHARMA LP (US) 2016-11-23 EP disclosed
WO-2012120099-A2 SMALL MOLECULE MODULATORS OF THE COLD AND MENTHOL RECEPTOR TRPM8 B.R.A.I.N. BIOTECHNOLOGY RESEARCH AND INFORMATION NETWORK AG (DE) 2012-09-13 WO disclosed
EP-2497458-A1 Small molecule modulators of the cold and menthol receptor TRPM8 B.R.A.I.N. Biotechnology Research And Information Network AG (DE) 2012-09-12 EP disclosed
WO-2012085648-A1 PHOSPHORUS-SUBSTITUTED QUINOXALINE-TYPE PIPERIDINE COMPOUNDS AND USES THEREOF PURDUE PHARMA L.P. (US) 2012-06-28 WO disclosed
EP-2433937-A1 Substituted-quinoxaline-type-piperidine compounds and the uses thereof Purdue Pharma LP (US) 2012-03-28 EP disclosed
EP-2433935-A1 Substituted-quinoxaline-type-piperidine compounds and the uses thereof Purdue Pharma LP (US) 2012-03-28 EP disclosed
EP-2433936-A1 Substituted-quinoxaline-type-piperidine compounds and the uses thereof Purdue Pharma LP (US) 2012-03-28 EP disclosed
EP-2120922-A2 COMPOSITIONS COMPRISING LAMIRIDOSIN, IRIDOIDS OR DERIVATIVES THEREOF FOR TREATMENT OF HEPATITIS C OR HEPATITIS B NY Financial (International) Corporation (VG) 2009-11-25 EP disclosed
EP-2086958-A2 SUBSTITUTED-QUINOXALINE-TYPE-PIPERIDINE COMPOUNDS AND THE USES THEREOF Purdue Pharma LP (US) 2009-08-12 EP disclosed
WO-2009027820-A2 SUBSTITUTED-QUINOXALINE-TYPE-PIPERIDINE COMPOUNDS AND THE USES THEREOF PURDUE PHARMA L.P. (DE) 2009-03-05 WO disclosed
WO-2008100547-A2 COMPOSITIONS COMPRISING LAMIRIDOSIN, IRIDOIDS OR DERIVATIVES THEREOF FOR TREATMENT OF HEPATITIS C OR HEPATITIS B NY FINANCIAL (INTERNATIONAL) CORPORATION (VG) 2008-08-21 WO disclosed