Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 12/20 | 0.76 |
| ▸ | MME | P08473 | 9/20 | 0.76 |
| ▸ | CPA1 | P15085 | 3/20 | 0.76 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.76 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7616915 | 0.88 | MME (0.68) | ACEMMECPA1ACE2FOLH1 | |
| SCHEMBL10174603 | 0.88 | MME (0.86) | ACEMMECPA1ACE2 | |
| SCHEMBL6465852 | 0.88 | MME (0.68) | ACEMMECPA1ACE2FOLH1 | |
| SCHEMBL4572624 | 0.86 | MME (0.67) | ACEMMECPA1ACE2FOLH1 | |
| SCHEMBL10425350 | 0.86 | MME (0.67) | ACEMMECPA1ACE2FOLH1 | |
| SCHEMBL24821176 | 0.86 | MME (0.67) | ACEMMECPA1ACE2FOLH1 | |
| SCHEMBL6163836 | 0.85 | MME (0.70) | ACEMMECPA1ACE2FOLH1 | |
| SCHEMBL16481670 | 0.85 | ACE (0.65) | ACEMMECPA1ACE2FOLH1 | |
| SCHEMBL2545591 | 0.85 | ACE (0.65) | ACEMMECPA1ACE2FOLH1 | |
| SCHEMBL4073351 | 0.85 | ACE (0.65) | ACEMMECPA1ACE2FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900197-A1 | BETA-THIOPROPIONYL-AMINOACID DERIVATIVES AND THEIR USE AS BETA-LACTAMASE INHIBITORS | SMITHKLINE BEECHAM PLC (GB) | 1999-03-10 | — | — | EP | claimed |
| WO-1997030027-A1 | BETA-THIOPROPIONYL-AMINOACID DERIVATIVES AND THEIR USE AS BETA-LACTAMASE INHIBITORS | SMITHKLINE BEECHAM PLC (GB) | 1997-08-21 | — | — | WO | claimed |