SCHEMBL8523181

SCHEMBL8523181

CC=CC(=O)OCCCCCCCCCCCCCC

nearest known ligand 0.70

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 4/20 0.70
ATM Q13315 1/20 0.67
NAAA Q02083 1/20 0.53
TSHR P16473 3/20 0.52
HPGD P15428 1/20 0.52
APP P05067 4/20 0.51
EPHX1 P07099 1/20 0.50
MAPT P10636 1/20 0.50
RAB9A P51151 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
HTT P42858 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
PRKCA P17252 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1337842 1.00 HCAR2 (0.70) HCAR2ATMNAAATSHRHPGD
SCHEMBL1337692 1.00 HCAR2 (0.70) HCAR2ATMNAAATSHRHPGD
SCHEMBL5176603 1.00 HCAR2 (0.70) HCAR2ATMNAAATSHRHPGD
SCHEMBL111970 1.00 HCAR2 (0.70) HCAR2ATMNAAATSHRHPGD
SCHEMBL1067418 1.00 HCAR2 (0.70) HCAR2ATMNAAATSHRHPGD
SCHEMBL1067419 1.00 HCAR2 (0.70) HCAR2ATMNAAATSHRHPGD
SCHEMBL10566535 1.00 HCAR2 (0.70) HCAR2ATMNAAATSHRHPGD
SCHEMBL1337844 1.00 HCAR2 (0.70) HCAR2ATMNAAATSHRHPGD
SCHEMBL8029495 1.00 HCAR2 (0.70) HCAR2ATMNAAATSHRHPGD
SCHEMBL5176599 1.00 HCAR2 (0.70) HCAR2ATMNAAATSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0691327-B1 AMINE DERIVATIVE AND DERMATOLOGIC PREPARATION CONTAINING THE SAME KAO CORP (JP) 1999-07-21 EP disclosed
US-5723497-A AMINE ALCOHOL DERIVATIVES FOR WRINKLE RESISTNCE KAO CORPORATION (JP) 1998-03-03 US disclosed
EP-0691327-A1 AMINE DERIVATIVE AND DERMATOLOGIC PREPARATION CONTAINING THE SAME Kao Corporation (JP) 1996-01-10 EP disclosed
US-4829111-A OLEFIN POLYMERS, WEATHERPROOFING, PIPERAZINE DERIVATIVE MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1989-05-09 US disclosed