Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | DRD4 | P21917 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31025920 | 0.79 | HSD17B10 (0.70) | ALDH1A1MAPTALOX15TSHRCHRM3 | |
| SCHEMBL18886833 | 0.79 | HSD17B10 (0.70) | ALDH1A1MAPTALOX15TSHRCHRM3 | |
| SCHEMBL9684170 | 0.75 | MEN1 (0.51) | ALDH1A1MAPTALOX15TSHRDRD2 | |
| SCHEMBL6014774 | 0.75 | KDM4E (0.61) | ALDH1A1MAPTHSD17B10KMT2AMEN1 | |
| SCHEMBL29612041 | 0.73 | CYP2C9 (0.58) | ALDH1A1MAPTALOX15TSHRCHRM3 | |
| SCHEMBL6964299 | 0.72 | KDM4E (0.57) | ALDH1A1MAPTHSD17B10KMT2AMEN1 | |
| SCHEMBL30602834 | 0.72 | KDM4E (0.57) | ALDH1A1MAPTHSD17B10KMT2AMEN1 | |
| SCHEMBL16880202 | 0.72 | HDAC6 (0.53) | ALDH1A1MAPTKMT2AGAAPARP1 | |
| SCHEMBL6768412 | 0.72 | HSD17B10 (0.51) | ALDH1A1MAPTALOX15HTTHSD17B10 | |
| SCHEMBL16880356 | 0.71 | MAPK1 (0.52) | ALDH1A1MAPTALOX15TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999043323-A1 | COMPOUNDS AND METHODS FOR CHEMOSENSITIZING MULTIDRUG RESISTANT CELLS | FOX CHASE CANCER CENTER (US) | 1999-09-02 | — | — | WO | disclosed |