Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 11/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 7/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8523505 | 0.85 | SRD5A1 (0.33) | SRD5A1SRD5A2CYP19A1GRIN1GRIN2B | |
| SCHEMBL8522969 | 0.83 | SRD5A1 (0.34) | SRD5A1SRD5A2 | |
| SCHEMBL8996698 | 0.83 | SRD5A1 (0.34) | SRD5A1SRD5A2 | |
| SCHEMBL8524175 | 0.80 | SRD5A1 (0.36) | SRD5A1SRD5A2CYP19A1 | |
| SCHEMBL8996747 | 0.80 | SRD5A1 (0.38) | SRD5A1SRD5A2CYP19A1 | |
| SCHEMBL8996732 | 0.80 | SRD5A1 (0.38) | SRD5A1SRD5A2CYP19A1 | |
| SCHEMBL8996729 | 0.80 | SRD5A1 (0.34) | SRD5A1SRD5A2 | |
| SCHEMBL8523250 | 0.79 | SRD5A1 (0.35) | SRD5A1SRD5A2 | |
| SCHEMBL8996758 | 0.78 | SRD5A1 (0.36) | MAPTSRD5A1SRD5A2CYP19A1 | |
| SCHEMBL8996766 | 0.78 | SRD5A1 (0.36) | MAPTSRD5A1SRD5A2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786999-A4 | COMBINATION METHOD FOR ACNE TREATMENT | MERCK & CO INC (US) | 1999-01-20 | — | — | EP | claimed |
| EP-0786999-A1 | COMBINATION METHOD FOR ACNE TREATMENT | Merck & Co., Inc. (US) | 1997-08-06 | — | — | EP | claimed |
| WO-1996012487-A1 | COMBINATION METHOD FOR ACNE TREATMENT | MERCK & CO., INC. (US) | 1996-05-02 | — | — | WO | claimed |