Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | THPO | P40225 | 1/20 | 0.54 |
| ▸ | MTOR | P42345 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CETP | P11597 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | UBE2N | P61088 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | LAP3 | P28838 | 2/20 | 0.48 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.47 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089181 | 1.00 | SPHK1 (0.58) | SPHK1CYP2D6LMNATP53GMNN | |
| SCHEMBL9208410 | 1.00 | SPHK1 (0.58) | SPHK1CYP2D6LMNATP53GMNN | |
| SCHEMBL10398801 | 1.00 | SPHK1 (0.58) | SPHK1CYP2D6LMNATP53GMNN | |
| SCHEMBL21414 | 1.00 | SPHK1 (0.58) | SPHK1CYP2D6LMNATP53GMNN | |
| Hydrochloric Acid SCHEMBL11508474 | 0.98 | SPHK1 (0.56) | SPHK1CYP2D6LMNATP53GMNN | |
| Hydrochloric Acid SCHEMBL4622842 | 0.98 | SPHK1 (0.56) | SPHK1CYP2D6LMNATP53GMNN | |
| Hydrochloric Acid SCHEMBL10706435 | 0.98 | SPHK1 (0.56) | SPHK1CYP2D6LMNATP53GMNN | |
| SCHEMBL11137785 | 0.97 | SPHK1 (0.54) | SPHK1CYP2D6LMNATP53GMNN | |
| SCHEMBL926446 | 0.91 | SPHK1 (0.54) | SPHK1CYP2D6LMNATP53GMNN | |
| SCHEMBL141849 | 0.90 | SPHK1 (0.44) | SPHK1CYP2D6LMNATP53GMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939554-A | Diarylaminopropanediol and diarylmethyl-oxazolidinone compounds | NDSU RESEARCH FOUNDATION (US) | 1999-08-17 | — | — | US | disclosed |
| US-5623087-A | Method for preparation of optically active diarylalanines | NDSU-RESEARCH FOUNDATION (US) | 1997-04-22 | — | — | US | disclosed |