SCHEMBL8523795

SCHEMBL8523795

O=C(NC(=O)c1c(F)cccc1F)Nc1ccc(OC(F)(F)C(F)C(F)(F)F)c(Cl)c1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 8/20 0.74
KMT2A Q03164 8/20 0.74
MAPT P10636 8/20 0.74
USP2 O75604 1/20 0.74
ALOX15 P16050 1/20 0.74
RECQL P46063 2/20 0.48
NPC1 O15118 7/20 0.45
RAB9A P51151 7/20 0.45
SMN1; SMN2 Q16637 6/20 0.45
HTT P42858 3/20 0.44
TDP1 Q9NUW8 2/20 0.44
POLB P06746 2/20 0.44
NPSR1 Q6W5P4 2/20 0.44
PKM P14618 1/20 0.44
KDM4E B2RXH2 2/20 0.43
GAA P10253 2/20 0.43
THRB P10828 1/20 0.43
HPGD P15428 1/20 0.43
GCGR P47871 1/20 0.42
ALDH1A1 P00352 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29828618 1.00 MEN1 (0.74) MEN1KMT2AMAPTUSP2ALOX15
SCHEMBL8659704 0.92 MEN1 (0.63) MEN1KMT2AMAPTUSP2ALOX15
Novaluron SCHEMBL29394806 0.89 MEN1 (0.60) MEN1KMT2AMAPTUSP2ALOX15
Novaluron SCHEMBL4137715 0.89 MEN1 (0.60) MEN1KMT2AMAPTUSP2ALOX15
Novaluron SCHEMBL26984 0.89 MEN1 (0.60) MEN1KMT2AMAPTUSP2ALOX15
SCHEMBL28713610 0.89 MAPT (0.60) MEN1KMT2AMAPTUSP2ALOX15
SCHEMBL13943025 0.88 MEN1 (0.59) MEN1KMT2AMAPTUSP2ALOX15
Lufenuron SCHEMBL7198368 0.88 MEN1 (0.77) MEN1KMT2AMAPTUSP2ALOX15
SCHEMBL7586417 0.87 MEN1 (0.68) MEN1KMT2AMAPTUSP2ALOX15
SCHEMBL13814849 0.86 MAPT (0.55) MEN1KMT2AMAPTUSP2ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114805140-A Preparation method of benzoyl urea anthelmintic 常州齐晖药业有限公司 2022-07-29 CN disclosed
WO-1999018796-A2 PESTICIDAL COMBINATION RHONE-POULENC AGRO (FR) 1999-04-22 WO disclosed