Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8466206 | 0.84 | MAPT (0.45) | MAPTHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL3708781 | 0.79 | MAPT (0.38) | MAPTHTTSMN1; SMN2TDP1NPSR1 | |
| SCHEMBL1021962 | 0.74 | MAPT (0.48) | MAPTHTTSMN1; SMN2NPSR1L3MBTL1 | |
| SCHEMBL935506 | 0.73 | MAPT (0.49) | MAPTHTTSMN1; SMN2NPSR1L3MBTL1 | |
| SCHEMBL489425 | 0.73 | MAPT (0.47) | MAPTHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL21296290 | 0.72 | TAAR1 (0.42) | L3MBTL1ALDH1A1LMNATAAR1 | |
| Hydrochloric Acid SCHEMBL17710427 | 0.71 | MAPT (0.46) | MAPTHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL9572777 | 0.70 | MAPT (0.44) | MAPTHTTSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL9407546 | 0.70 | TDP1 (0.45) | MAPTHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL20694856 | 0.68 | MAPT (0.44) | MAPTHTTSMN1; SMN2TDP1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0676403-B1 | Arylaminosilane end-capped urethane sealants | WITCO CORP (US) | 1999-09-15 | — | — | EP | disclosed |
| EP-0676403-A1 | Arylaminosilane end-capped urethane sealants | OSI SPECIALTIES, INC. (US) | 1995-10-11 | — | — | EP | disclosed |