Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.41 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 6/20 | 0.38 |
| ▸ | PPARA | Q07869 | 6/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TLR2 | O60603 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | FABP4 | P15090 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10973416 | 1.00 | ACE2 (0.42) | ACE2GPR84FFAR1PPARDMAPT | |
| SCHEMBL8523775 | 1.00 | ACE2 (0.42) | ACE2GPR84FFAR1PPARDMAPT | |
| SCHEMBL9839518 | 0.98 | ACE2 (0.46) | ACE2GPR84FFAR1PPARDMAPT | |
| SCHEMBL7770712 | 0.98 | ACE2 (0.46) | ACE2GPR84FFAR1PPARDMAPT | |
| SCHEMBL28856640 | 0.98 | ACE2 (0.46) | ACE2GPR84FFAR1PPARDMAPT | |
| SCHEMBL11137702 | 0.98 | ACE2 (0.46) | ACE2GPR84FFAR1PPARDMAPT | |
| SCHEMBL7770709 | 0.98 | ACE2 (0.46) | ACE2GPR84FFAR1PPARDMAPT | |
| SCHEMBL9839621 | 0.98 | ACE2 (0.46) | ACE2GPR84FFAR1PPARDMAPT | |
| SCHEMBL28856639 | 0.98 | ACE2 (0.46) | ACE2GPR84FFAR1PPARDMAPT | |
| SCHEMBL28303043 | 0.98 | ACE2 (0.46) | ACE2GPR84FFAR1PPARDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5623087-A | Method for preparation of optically active diarylalanines | NDSU-RESEARCH FOUNDATION (US) | 1997-04-22 | — | — | US | claimed |
| US-5939554-A | Diarylaminopropanediol and diarylmethyl-oxazolidinone compounds | NDSU RESEARCH FOUNDATION (US) | 1999-08-17 | — | — | US | disclosed |
| US-5623087-A | Method for preparation of optically active diarylalanines | NDSU-RESEARCH FOUNDATION (US) | 1997-04-22 | — | — | US | disclosed |