Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | NQO1 | P15559 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28345506 | 0.90 | FASN (0.43) | CLK1DYRK1AKDM4EALDH1A1GAA | |
| SCHEMBL20561997 | 0.81 | CLK1 (0.44) | CLK1DYRK1AKDM4EALDH1A1GAA | |
| SCHEMBL20563958 | 0.81 | CLK1 (0.44) | CLK1DYRK1AKDM4EALDH1A1GAA | |
| SCHEMBL10338293 | 0.79 | KDM4E (0.59) | CLK1DYRK1AKDM4EALDH1A1GAA | |
| SCHEMBL11309875 | 0.78 | ERN1 (0.49) | CLK1DYRK1AKDM4EALDH1A1GAA | |
| SCHEMBL151389 | 0.75 | NCOA3 (0.65) | CLK1DYRK1AKDM4EALDH1A1GAA | |
| SCHEMBL31588629 | 0.75 | NCOA3 (0.65) | CLK1DYRK1AKDM4EALDH1A1GAA | |
| SCHEMBL31588569 | 0.74 | ESR2 (0.59) | CLK1DYRK1AKDM4EALDH1A1GAA | |
| SCHEMBL8913792 | 0.74 | ESR2 (0.59) | CLK1DYRK1AKDM4EALDH1A1GAA | |
| SCHEMBL29614953 | 0.74 | ESR2 (0.59) | CLK1DYRK1AKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0938488-A1 | PHOSPHINE LIGANDS | OXFORD ASYMMETRY INTERNATIONAL PLC (GB) | 1999-09-01 | — | — | EP | disclosed |
| WO-1998012202-A1 | PHOSPHINE LIGANDS | OXFORD ASYMMETRY INTERNATIONAL PLC. (GB) | 1998-03-26 | — | — | WO | disclosed |