Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9618891 | 0.90 | POLB (0.47) | POLBCHRM3CYP2C19KCNH2CHRM2 | |
| SCHEMBL9809558 | 0.89 | CHRM3 (0.55) | POLBCHRM3CYP2C19KCNH2CHRM2 | |
| SCHEMBL7919652 | 0.89 | CHRM3 (0.53) | POLBCHRM3CYP2C19KCNH2CHRM2 | |
| Water SCHEMBL9618799 | 0.88 | CHRM3 (0.54) | POLBCHRM3CYP2C19KCNH2CHRM2 | |
| SCHEMBL9809560 | 0.88 | CHRM3 (0.53) | POLBCHRM3CYP2C19KCNH2CHRM2 | |
| SCHEMBL9809464 | 0.88 | CHRM3 (0.55) | POLBCHRM3CYP2C19KCNH2CHRM2 | |
| SCHEMBL7913118 | 0.88 | CHRM3 (0.55) | POLBCHRM3CYP2C19KCNH2CHRM2 | |
| SCHEMBL9809567 | 0.88 | CHRM3 (0.55) | POLBCHRM3CYP2C19KCNH2CHRM2 | |
| SCHEMBL8338552 | 0.88 | CHRM2 (0.59) | POLBCHRM3CYP2C19KCNH2CHRM2 | |
| SCHEMBL9618822 | 0.87 | CHRM3 (0.48) | POLBCHRM3CYP2C19KCNH2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915826-A4 | SMOOTH MUSCLE SPASMOLYTIC AGENTS, COMPOSITIONS AND METHODS OF USE THEREOF | BRIDGE PHARMA INC (US) | 1999-12-29 | — | — | EP | disclosed |
| EP-0915826-A1 | SMOOTH MUSCLE SPASMOLYTIC AGENTS, COMPOSITIONS AND METHODS OF USE THEREOF | Bridge Pharma, Inc. (US) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998000390-A1 | SMOOTH MUSCLE SPASMOLYTIC AGENTS, COMPOSITIONS AND METHODS OF USE THEREOF | BRIDGE PHARMA, INC. (US) | 1998-01-08 | — | — | WO | disclosed |
| US-5036107-A | Treatment of neurogenic bladder disorders | MARION MERRELL DOW INC. (US) | 1991-07-30 | — | — | US | disclosed |