Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | CDC25A | P30304 | 4/20 | 0.41 |
| ▸ | CDC25B | P30305 | 4/20 | 0.41 |
| ▸ | CDC25C | P30307 | 4/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | EIF4E | P06730 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CASP2 | P42575 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8524942 | 0.95 | CDC25A (0.43) | KMT2AKDM4EARCDC25ACDC25B | |
| SCHEMBL8523909 | 0.90 | CDC25A (0.44) | KMT2AKDM4EARCDC25ACDC25B | |
| Hydrochloric Acid SCHEMBL8525329 | 0.85 | SMN1; SMN2 (0.45) | KMT2AKDM4EARCDC25ACDC25B | |
| SCHEMBL8485449 | 0.85 | CDC25A (0.46) | KMT2AKDM4ECDC25ACDC25BCDC25C | |
| SCHEMBL8525405 | 0.83 | CDC25A (0.51) | KMT2AKDM4EARCDC25ACDC25B | |
| SCHEMBL8525234 | 0.83 | CDC25A (0.46) | KMT2AKDM4EARCDC25ACDC25B | |
| Hydrochloric Acid SCHEMBL8525371 | 0.82 | CDC25A (0.48) | KDM4ECDC25ACDC25BCDC25CDUSP3 | |
| SCHEMBL8486825 | 0.81 | CDC25A (0.44) | KMT2AKDM4EARCDC25ACDC25B | |
| SCHEMBL8483711 | 0.81 | CDC25A (0.46) | KMT2AKDM4EARCDC25ACDC25B | |
| SCHEMBL8524659 | 0.80 | CYP19A1 (0.48) | KMT2AKDM4ECDC25ACDC25BCDC25C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999015524-A1 | THIAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-04-01 | — | — | WO | disclosed |