Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 12/20 | 0.57 |
| ▸ | S1PR3 | Q99500 | 8/20 | 0.57 |
| ▸ | S1PR4 | O95977 | 6/20 | 0.57 |
| ▸ | S1PR5 | Q9H228 | 6/20 | 0.57 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.57 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.57 |
| ▸ | GPR183 | P32249 | 1/20 | 0.57 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.57 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.50 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.50 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8496107 | 0.88 | S1PR1 (0.58) | S1PR1S1PR3S1PR4S1PR5TNNC1 | |
| SCHEMBL8499382 | 0.88 | S1PR1 (0.58) | S1PR1S1PR3S1PR4S1PR5TNNC1 | |
| SCHEMBL8497910 | 0.88 | S1PR1 (0.58) | S1PR1S1PR3S1PR4S1PR5TNNC1 | |
| SCHEMBL8496719 | 0.88 | S1PR1 (0.58) | S1PR1S1PR3S1PR4S1PR5TNNC1 | |
| Hydrochloric Acid SCHEMBL6245642 | 0.86 | S1PR1 (0.59) | S1PR1S1PR3S1PR4S1PR5TNNC1 | |
| SCHEMBL8498823 | 0.86 | S1PR1 (0.60) | S1PR1S1PR3S1PR4S1PR5TNNC1 | |
| SCHEMBL3394788 | 0.86 | S1PR1 (0.56) | S1PR1S1PR3S1PR4S1PR5TNNC1 | |
| SCHEMBL5993596 | 0.86 | FFAR1 (0.57) | S1PR1S1PR3S1PR4S1PR5TNNC1 | |
| SCHEMBL3392638 | 0.86 | S1PR1 (0.56) | S1PR1S1PR3S1PR4S1PR5TNNC1 | |
| SCHEMBL8496393 | 0.86 | S1PR1 (0.60) | S1PR1S1PR3S1PR4S1PR5TNNC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952316-A | FOR TREATING AUTOIMMUNE DISEASES, E.G., RHEUMATIOD ARTHRITIS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-09-14 | — | — | US | disclosed |
| US-5719176-A | 2-amino-1,3-propanediol compound and immunosuppressant | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-02-17 | — | — | US | disclosed |