SCHEMBL8525924

SCHEMBL8525924

Nc1cccc2c1CC(N1CCC(c3ccccc3)CC1)C(O)C2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ SLC18A3 Q16572 10/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29793983 1.00 SLC18A3 (1.00) SLC18A3
SCHEMBL8525923 1.00 SLC18A3 (1.00) SLC18A3
SCHEMBL24458291 0.96 SLC18A3 (1.00) SLC18A3
SCHEMBL29794043 0.96 SLC18A3 (1.00) SLC18A3
SCHEMBL21104710 0.86 SLC18A3 (0.75) SLC18A3
SCHEMBL29752590 0.86 SLC18A3 (0.75) SLC18A3
SCHEMBL24458282 0.86 SLC18A3 (0.75) SLC18A3
SCHEMBL24458334 0.86 SLC18A3 (0.75) SLC18A3
SCHEMBL8527217 0.86 SLC18A3 (0.75) SLC18A3
SCHEMBL18211383 0.86 SLC18A3 (0.75) SLC18A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022106714-A1 RADIOLABELLED COMPOUNDS FOR DIAGNOSING CHOLINERGIC NEURODEGENERATIVE DISEASES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2022-05-27 — — WO disclosed
EP-0648130-B1 RADIOIODINATED BENZOVESAMICOL ANALOGS FOR CHOLINERGIC NERVE MAPPING UNIV MICHIGAN (US) 1998-12-30 — — EP disclosed
EP-0648130-A1 RADIOIODINATED BENZOVESAMICOL ANALOGS FOR CHOLINERGIC NERVE MAPPING THE UNIVERSITY OF MICHIGAN (US) 1995-04-19 — — EP disclosed
EP-0648130-A4 RADIOIODINATED BENZOVESAMICOL ANALOGS FOR CHOLINERGIC NERVE MAPPING. UNIV MICHIGAN (US) 1994-01-26 — — EP disclosed
WO-1991017776-A1 RADIOIODINATED BENZOVESAMICOL ANALOGS FOR CHOLINERGIC NERVE MAPPING THE UNIVERSITY OF MICHIGAN (US) 1991-11-28 — — WO disclosed
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